LRP3 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	3 studies	27% ± 14%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of LRP3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	4146.22	245 / 245	99%	47.03	499 / 502
brain	99%	7499.79	2610 / 2642	100%	44.65	703 / 705
ovary	100%	9158.77	180 / 180	96%	38.88	414 / 430
breast	100%	3264.14	459 / 459	96%	22.59	1074 / 1118
adrenal gland	100%	3827.73	258 / 258	95%	45.30	218 / 230
liver	100%	3049.85	226 / 226	92%	25.40	375 / 406
thymus	100%	3116.32	652 / 653	89%	17.10	541 / 605
stomach	96%	1907.39	344 / 359	88%	24.68	252 / 286
pancreas	96%	1324.33	316 / 328	87%	13.90	154 / 178
lung	97%	1686.75	559 / 578	84%	16.37	971 / 1155
bladder	95%	3295.29	20 / 21	85%	18.91	427 / 504
intestine	95%	2474.63	915 / 966	85%	21.01	448 / 527
uterus	99%	3266.08	169 / 170	75%	17.62	343 / 459
esophagus	89%	2801.47	1289 / 1445	74%	18.90	136 / 183
skin	98%	1818.82	1770 / 1809	60%	13.19	284 / 472
kidney	82%	1167.87	73 / 89	64%	10.01	577 / 901
adipose	100%	3641.84	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	33.66	80 / 80
ureter	0%	0	0 / 0	100%	7.61	1 / 1
blood vessel	99%	2802.07	1325 / 1335	0%	0	0 / 0
muscle	98%	1994.35	790 / 803	0%	0	0 / 0
heart	95%	1680.16	817 / 861	0%	0	0 / 0
spleen	82%	945.47	197 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	51%	6.62	23 / 45
peripheral blood	23%	236.50	210 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0010628	Biological process	positive regulation of gene expression
GO_0045599	Biological process	negative regulation of fat cell differentiation
GO_0045669	Biological process	positive regulation of osteoblast differentiation
GO_0010629	Biological process	negative regulation of gene expression
GO_0006898	Biological process	receptor-mediated endocytosis
GO_0150104	Biological process	transport across blood-brain barrier
GO_0005905	Cellular component	clathrin-coated pit
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane

Gene name	LRP3
Protein name	Low-density lipoprotein receptor-related protein 3 (LRP-3) (105 kDa low-density lipoprotein receptor-related protein) (hLRp105) LDL receptor related protein 3
Synonyms
Description	FUNCTION: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.
Accessions	ENST00000253193.9 O75074 V9GYG8 ENST00000592484.5

LRP3 report