Insufficient scRNA-seq data for expression of LORICRIN at single-cell level.
Insufficient scRNA-seq data for expression of LORICRIN at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 83% | 57528.04 | 1503 / 1809 | 12% | 30.71 | 55 / 472 |
| esophagus | 68% | 25.49 | 988 / 1445 | 22% | 1.96 | 40 / 183 |
| brain | 77% | 31.85 | 2031 / 2642 | 9% | 0.19 | 63 / 705 |
| ovary | 77% | 26.14 | 139 / 180 | 2% | 0.06 | 8 / 430 |
| spleen | 73% | 22.10 | 176 / 241 | 0% | 0 | 0 / 0 |
| muscle | 70% | 37.43 | 566 / 803 | 0% | 0 | 0 / 0 |
| breast | 67% | 22.60 | 309 / 459 | 2% | 3.46 | 23 / 1118 |
| blood vessel | 69% | 65.80 | 915 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 68% | 48.98 | 821 / 1204 | 0% | 0 | 0 / 0 |
| lung | 57% | 28.29 | 332 / 578 | 7% | 0.38 | 81 / 1155 |
| heart | 63% | 19.90 | 542 / 861 | 0% | 0 | 0 / 0 |
| intestine | 59% | 20.95 | 573 / 966 | 1% | 0.33 | 5 / 527 |
| peripheral blood | 57% | 19.48 | 534 / 929 | 0% | 0 | 0 / 0 |
| uterus | 45% | 13.39 | 77 / 170 | 10% | 0.92 | 48 / 459 |
| thymus | 51% | 18.80 | 336 / 653 | 1% | 0.03 | 7 / 605 |
| prostate | 47% | 12.62 | 116 / 245 | 0% | 0.00 | 1 / 502 |
| stomach | 45% | 13.20 | 162 / 359 | 1% | 0.01 | 2 / 286 |
| pancreas | 43% | 16.84 | 142 / 328 | 2% | 0.07 | 3 / 178 |
| adrenal gland | 43% | 14.07 | 110 / 258 | 2% | 0.05 | 5 / 230 |
| liver | 40% | 23.26 | 91 / 226 | 0% | 0.98 | 2 / 406 |
| kidney | 28% | 7.38 | 25 / 89 | 0% | 0.00 | 1 / 901 |
| tonsil | 0% | 0 | 0 / 0 | 22% | 0.97 | 10 / 45 |
| bladder | 14% | 2.76 | 3 / 21 | 7% | 0.92 | 37 / 504 |
| lymph node | 0% | 0 | 0 / 0 | 14% | 0.22 | 4 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0030216 | Biological process | keratinocyte differentiation |
| GO_0031424 | Biological process | keratinization |
| GO_0018149 | Biological process | peptide cross-linking |
| GO_0007010 | Biological process | cytoskeleton organization |
| GO_0001533 | Cellular component | cornified envelope |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005200 | Molecular function | structural constituent of cytoskeleton |
| GO_0030280 | Molecular function | structural constituent of skin epidermis |
| GO_0005515 | Molecular function | protein binding |
| Gene name | LORICRIN |
| Protein name | LOR protein Loricrin |
| Synonyms | LOR LRN |
| Description | FUNCTION: Major keratinocyte cell envelope protein. |
| Accessions | P23490 Q6FHY3 ENST00000368742.4 |