LHFPL4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1905702Biological processregulation of inhibitory synapse assembly
GO_0007605Biological processsensory perception of sound
GO_0099645Biological processneurotransmitter receptor localization to postsynaptic specialization membrane
GO_0097112Biological processgamma-aminobutyric acid receptor clustering
GO_0099572Cellular componentpostsynaptic specialization
GO_0098982Cellular componentGABA-ergic synapse
GO_0060077Cellular componentinhibitory synapse
GO_0005886Cellular componentplasma membrane
GO_0045211Cellular componentpostsynaptic membrane
GO_0030425Cellular componentdendrite
GO_0050811Molecular functionGABA receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameLHFPL4
Protein nameLHFPL tetraspan subfamily member 4 protein (GABAA receptor regulatory Lhfpl4) (Lipoma HMGIC fusion partner-like 4 protein)
SynonymsGARLH4
DescriptionFUNCTION: Plays a role in the regulation of inhibitory synapse formation and function by being involved in maintening gamma-aminobutyric acid receptors (GABAARs) clustering and their associated scaffold proteins at inhibitory synaptic sites. Acts in concert with NLGN2 to recruit or stabilize GABAARs. .

AccessionsQ7Z7J7
ENST00000287585.8