LDLRAD3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0070613Biological processregulation of protein processing
GO_0006898Biological processreceptor-mediated endocytosis
GO_0005886Cellular componentplasma membrane
GO_0001540Molecular functionamyloid-beta binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameLDLRAD3
Protein nameLow density lipoprotein receptor class A domain containing 3
Low-density lipoprotein receptor class A domain-containing protein 3 (LDLR class A domain-containing protein 3)
SynonymsLRAD3
DescriptionFUNCTION: May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. May regulate ITCH and NEDD4 E3 ligase activity and degradation . .; FUNCTION: (Microbial infection) Acts as a receptor for Venezuelan equine encephalitis virus. .

AccessionsENST00000528989.5 [Q86YD5-2]
E9PR86
ENST00000315571.6 [Q86YD5-1]
ENST00000524419.5
Q86YD5