LCE3B report

I. Expression across cell types

Insufficient scRNA-seq data for expression of LCE3B at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LCE3B at tissue level.

III. Associated gene sets

GO_0050829Biological processdefense response to Gram-negative bacterium
GO_0031640Biological processkilling of cells of another organism
GO_0031424Biological processkeratinization
GO_0050830Biological processdefense response to Gram-positive bacterium
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameLCE3B
Protein nameLate cornified envelope protein 3B (Late envelope protein 14)
SynonymsLEP14
DescriptionFUNCTION: A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens . .

AccessionsENST00000335633.1
Q5TA77