Insufficient scRNA-seq data for expression of LCE3A at single-cell level.
Insufficient scRNA-seq data for expression of LCE3A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
tonsil | 0% | 0 | 0 / 0 | 67% | 16.47 | 30 / 45 |
esophagus | 20% | 4.39 | 286 / 1445 | 29% | 6.31 | 53 / 183 |
skin | 40% | 6.12 | 718 / 1809 | 8% | 6.73 | 39 / 472 |
breast | 22% | 1.30 | 102 / 459 | 2% | 0.13 | 21 / 1118 |
adipose | 23% | 0.92 | 275 / 1204 | 0% | 0 | 0 / 0 |
uterus | 1% | 3.16 | 2 / 170 | 15% | 4.46 | 68 / 459 |
lung | 0% | 0.01 | 1 / 578 | 14% | 2.90 | 163 / 1155 |
ovary | 8% | 0.21 | 15 / 180 | 1% | 0.04 | 3 / 430 |
bladder | 5% | 0.10 | 1 / 21 | 4% | 0.88 | 19 / 504 |
liver | 5% | 0.13 | 11 / 226 | 0% | 0 | 0 / 406 |
muscle | 4% | 0.09 | 33 / 803 | 0% | 0 | 0 / 0 |
thymus | 1% | 0.02 | 8 / 653 | 1% | 0.10 | 8 / 605 |
brain | 2% | 0.05 | 61 / 2642 | 0% | 0 | 0 / 705 |
peripheral blood | 2% | 0.06 | 19 / 929 | 0% | 0 | 0 / 0 |
intestine | 1% | 0.02 | 7 / 966 | 1% | 0.27 | 6 / 527 |
blood vessel | 1% | 0.03 | 17 / 1335 | 0% | 0 | 0 / 0 |
kidney | 1% | 0.02 | 1 / 89 | 0% | 0.01 | 1 / 901 |
stomach | 1% | 0.02 | 3 / 359 | 0% | 0 | 0 / 286 |
heart | 1% | 0.02 | 6 / 861 | 0% | 0 | 0 / 0 |
spleen | 0% | 0.01 | 1 / 241 | 0% | 0 | 0 / 0 |
prostate | 0% | 0.01 | 1 / 245 | 0% | 0 | 0 / 502 |
pancreas | 0% | 0.01 | 1 / 328 | 0% | 0 | 0 / 178 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050829 | Biological process | defense response to Gram-negative bacterium |
GO_0031640 | Biological process | killing of cells of another organism |
GO_0031424 | Biological process | keratinization |
GO_0050830 | Biological process | defense response to Gram-positive bacterium |
GO_0005515 | Molecular function | protein binding |
Gene name | LCE3A |
Protein name | Late cornified envelope protein 3A (Late envelope protein 13) |
Synonyms | LEP13 |
Description | FUNCTION: A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens . . |
Accessions | Q5TA76 ENST00000335674.1 |