Insufficient scRNA-seq data for expression of LCE3A at single-cell level.
Insufficient scRNA-seq data for expression of LCE3A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| tonsil | 0% | 0 | 0 / 0 | 67% | 16.47 | 30 / 45 |
| esophagus | 20% | 4.39 | 286 / 1445 | 29% | 6.31 | 53 / 183 |
| skin | 40% | 6.12 | 718 / 1809 | 8% | 6.73 | 39 / 472 |
| breast | 22% | 1.30 | 102 / 459 | 2% | 0.13 | 21 / 1118 |
| adipose | 23% | 0.92 | 275 / 1204 | 0% | 0 | 0 / 0 |
| uterus | 1% | 3.16 | 2 / 170 | 15% | 4.46 | 68 / 459 |
| lung | 0% | 0.01 | 1 / 578 | 14% | 2.90 | 163 / 1155 |
| ovary | 8% | 0.21 | 15 / 180 | 1% | 0.04 | 3 / 430 |
| bladder | 5% | 0.10 | 1 / 21 | 4% | 0.88 | 19 / 504 |
| liver | 5% | 0.13 | 11 / 226 | 0% | 0 | 0 / 406 |
| muscle | 4% | 0.09 | 33 / 803 | 0% | 0 | 0 / 0 |
| thymus | 1% | 0.02 | 8 / 653 | 1% | 0.10 | 8 / 605 |
| brain | 2% | 0.05 | 61 / 2642 | 0% | 0 | 0 / 705 |
| peripheral blood | 2% | 0.06 | 19 / 929 | 0% | 0 | 0 / 0 |
| intestine | 1% | 0.02 | 7 / 966 | 1% | 0.27 | 6 / 527 |
| blood vessel | 1% | 0.03 | 17 / 1335 | 0% | 0 | 0 / 0 |
| kidney | 1% | 0.02 | 1 / 89 | 0% | 0.01 | 1 / 901 |
| stomach | 1% | 0.02 | 3 / 359 | 0% | 0 | 0 / 286 |
| heart | 1% | 0.02 | 6 / 861 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0.01 | 1 / 241 | 0% | 0 | 0 / 0 |
| prostate | 0% | 0.01 | 1 / 245 | 0% | 0 | 0 / 502 |
| pancreas | 0% | 0.01 | 1 / 328 | 0% | 0 | 0 / 178 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0050829 | Biological process | defense response to Gram-negative bacterium |
| GO_0031640 | Biological process | killing of cells of another organism |
| GO_0031424 | Biological process | keratinization |
| GO_0050830 | Biological process | defense response to Gram-positive bacterium |
| GO_0005515 | Molecular function | protein binding |
| Gene name | LCE3A |
| Protein name | Late cornified envelope protein 3A (Late envelope protein 13) |
| Synonyms | LEP13 |
| Description | FUNCTION: A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens . . |
| Accessions | Q5TA76 ENST00000335674.1 |