Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 7 studies | 22% ± 7% | |
| astrocyte | 6 studies | 30% ± 12% | |
| macrophage | 4 studies | 19% ± 1% | |
| GABAergic neuron | 4 studies | 41% ± 16% | |
| glutamatergic neuron | 4 studies | 48% ± 18% | |
| microglial cell | 3 studies | 20% ± 1% | |
| oligodendrocyte precursor cell | 3 studies | 25% ± 4% | |
| endothelial cell of lymphatic vessel | 3 studies | 18% ± 2% | |
| transit amplifying cell | 3 studies | 25% ± 11% | |
| interneuron | 3 studies | 40% ± 19% | |
| oligodendrocyte | 3 studies | 23% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 36% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 1819.01 | 2639 / 2642 | 100% | 12.86 | 703 / 705 |
| esophagus | 100% | 1143.74 | 1445 / 1445 | 99% | 7.43 | 182 / 183 |
| breast | 100% | 1062.17 | 459 / 459 | 99% | 8.67 | 1111 / 1118 |
| stomach | 100% | 958.92 | 359 / 359 | 99% | 10.74 | 284 / 286 |
| intestine | 100% | 1246.08 | 966 / 966 | 99% | 11.77 | 523 / 527 |
| prostate | 100% | 1149.06 | 245 / 245 | 99% | 9.97 | 498 / 502 |
| skin | 100% | 1490.15 | 1808 / 1809 | 99% | 10.64 | 468 / 472 |
| ovary | 100% | 1111.12 | 180 / 180 | 99% | 6.56 | 425 / 430 |
| lung | 100% | 917.28 | 576 / 578 | 99% | 6.32 | 1140 / 1155 |
| bladder | 100% | 1116.29 | 21 / 21 | 98% | 8.48 | 494 / 504 |
| thymus | 100% | 1184.37 | 653 / 653 | 97% | 6.59 | 589 / 605 |
| uterus | 100% | 1284.18 | 170 / 170 | 96% | 7.36 | 442 / 459 |
| pancreas | 98% | 551.78 | 323 / 328 | 98% | 5.54 | 174 / 178 |
| kidney | 100% | 1500.98 | 89 / 89 | 94% | 7.03 | 843 / 901 |
| liver | 100% | 1149.22 | 226 / 226 | 91% | 4.67 | 369 / 406 |
| adrenal gland | 100% | 1836.84 | 258 / 258 | 88% | 4.96 | 203 / 230 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 7.53 | 29 / 29 |
| spleen | 100% | 1115.32 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.58 | 1 / 1 |
| muscle | 100% | 947.16 | 802 / 803 | 0% | 0 | 0 / 0 |
| adipose | 100% | 975.64 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 749.47 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| heart | 97% | 1234.44 | 836 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 6.99 | 43 / 45 |
| eye | 0% | 0 | 0 / 0 | 91% | 4.30 | 73 / 80 |
| peripheral blood | 60% | 840.53 | 560 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006429 | Biological process | leucyl-tRNA aminoacylation |
| GO_0106074 | Biological process | aminoacyl-tRNA metabolism involved in translational fidelity |
| GO_0006418 | Biological process | tRNA aminoacylation for protein translation |
| GO_0032543 | Biological process | mitochondrial translation |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0004823 | Molecular function | leucine-tRNA ligase activity |
| GO_0002161 | Molecular function | aminoacyl-tRNA editing activity |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | LARS2 |
| Protein name | leucine--tRNA ligase (EC 6.1.1.4) Leucyl-tRNA synthetase 2, mitochondrial Leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS) |
| Synonyms | KIAA0028 |
| Description | FUNCTION: Catalyzes the attachment of leucine to its cognate tRNA. . |
| Accessions | C9JYR8 ENST00000651549.1 A0A499FJL2 ENST00000430399.1 E9PHM2 A0A2R8Y581 Q15031 A0A494C1E0 ENST00000265537.8 A0A494C1K2 ENST00000414984.5 ENST00000650792.2 ENST00000652135.1 ENST00000485461.1 ENST00000642274.1 ENST00000645846.2 |