LARP6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032967Biological processpositive regulation of collagen biosynthetic process
GO_0006417Biological processregulation of translation
GO_0006396Biological processRNA processing
GO_0005737Cellular componentcytoplasm
GO_1990904Cellular componentribonucleoprotein complex
GO_0005634Cellular componentnucleus
GO_1990825Molecular functionsequence-specific mRNA binding
GO_0017022Molecular functionmyosin binding
GO_0035613Molecular functionRNA stem-loop binding
GO_0048027Molecular functionmRNA 5'-UTR binding
GO_0005515Molecular functionprotein binding
GO_0003729Molecular functionmRNA binding

IV. Literature review

[source]
Gene nameLARP6
Protein nameLa-related protein 6 (Acheron) (Achn) (La ribonucleoprotein domain family member 6)
La ribonucleoprotein 6, translational regulator
Synonyms
DescriptionFUNCTION: Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9. .

AccessionsENST00000299213.10 [Q9BRS8-1]
ENST00000344870.4 [Q9BRS8-2]
Q9BRS8
ENST00000559316.2
ENST00000559140.2
H0YMC6
K7EPD2