Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 22 studies | 24% ± 7% | |
| classical monocyte | 19 studies | 27% ± 13% | |
| non-classical monocyte | 14 studies | 27% ± 13% | |
| conventional dendritic cell | 13 studies | 25% ± 12% | |
| monocyte | 12 studies | 22% ± 6% | |
| alveolar macrophage | 7 studies | 24% ± 6% | |
| mast cell | 6 studies | 26% ± 8% | |
| myeloid cell | 6 studies | 29% ± 12% | |
| dendritic cell | 6 studies | 33% ± 15% | |
| endothelial cell | 5 studies | 19% ± 3% | |
| mononuclear phagocyte | 5 studies | 24% ± 6% | |
| epithelial cell | 5 studies | 23% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 942.85 | 1445 / 1445 | 100% | 13.74 | 183 / 183 |
| kidney | 100% | 1188.75 | 89 / 89 | 100% | 19.16 | 901 / 901 |
| liver | 100% | 1633.36 | 226 / 226 | 100% | 22.90 | 406 / 406 |
| stomach | 100% | 777.92 | 359 / 359 | 100% | 15.80 | 286 / 286 |
| lung | 100% | 1819.86 | 578 / 578 | 100% | 18.38 | 1154 / 1155 |
| intestine | 100% | 1056.97 | 966 / 966 | 100% | 17.31 | 526 / 527 |
| uterus | 100% | 726.19 | 170 / 170 | 100% | 15.06 | 458 / 459 |
| breast | 100% | 1145.03 | 459 / 459 | 100% | 21.13 | 1115 / 1118 |
| bladder | 100% | 881.19 | 21 / 21 | 100% | 16.92 | 502 / 504 |
| thymus | 100% | 805.52 | 652 / 653 | 100% | 11.29 | 602 / 605 |
| prostate | 100% | 773.03 | 244 / 245 | 100% | 16.68 | 500 / 502 |
| skin | 100% | 1542.86 | 1808 / 1809 | 99% | 20.38 | 466 / 472 |
| ovary | 100% | 656.84 | 180 / 180 | 98% | 8.98 | 423 / 430 |
| adrenal gland | 100% | 2321.18 | 258 / 258 | 98% | 15.40 | 226 / 230 |
| pancreas | 98% | 592.27 | 321 / 328 | 100% | 21.00 | 178 / 178 |
| brain | 97% | 552.61 | 2569 / 2642 | 100% | 11.26 | 705 / 705 |
| adipose | 100% | 1521.77 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 30.89 | 29 / 29 |
| muscle | 100% | 2477.36 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1650.24 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 15.22 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.44 | 1 / 1 |
| blood vessel | 100% | 1057.43 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 95% | 1584.69 | 887 / 929 | 0% | 0 | 0 / 0 |
| heart | 95% | 1105.04 | 822 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 79% | 6.70 | 63 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0019216 | Biological process | regulation of lipid metabolic process |
| GO_0006629 | Biological process | lipid metabolic process |
| GO_0006508 | Biological process | proteolysis |
| GO_0005829 | Cellular component | cytosol |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0008233 | Molecular function | peptidase activity |
| GO_0042802 | Molecular function | identical protein binding |
| Gene name | LACTB |
| Protein name | Lactamase beta Serine beta-lactamase-like protein LACTB, mitochondrial (EC 3.4.-.-) |
| Synonyms | MRPL56 UNQ843/PRO1781 |
| Description | FUNCTION: Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism . Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism . It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein . Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism . . |
| Accessions | ENST00000261893.9 [P83111-1] P83111 H0YNN5 ENST00000413507.3 [P83111-2] ENST00000557972.1 |