KRTAP4-12 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KRTAP4-12 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KRTAP4-12 at tissue level.

III. Associated gene sets

GO_0005829Cellular componentcytosol
GO_0045095Cellular componentkeratin filament
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKRTAP4-12
Protein nameKeratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12)
KRTAP4-12 protein
SynonymsKAP4.12
KRTAP4.12
DescriptionFUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

AccessionsQ495H9
ENST00000394014.2
ENST00000709603.1
Q9BQ66
ENST00000571271.1