KRTAP4-1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KRTAP4-1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KRTAP4-1 at tissue level.

III. Associated gene sets

GO_0005829Cellular componentcytosol
GO_0045095Cellular componentkeratin filament
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKRTAP4-1
Protein nameKeratin-associated protein 4-1 (Keratin-associated protein 4-10) (Keratin-associated protein 4.1) (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10)
SynonymsKRTAP4.1
KRTAP4-10
KRTAP4.10
KAP4.10
DescriptionFUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

AccessionsQ9BYQ7
ENST00000398472.2