Insufficient scRNA-seq data for expression of KRTAP2-3 at single-cell level.
Insufficient scRNA-seq data for expression of KRTAP2-3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 48% | 253.32 | 861 / 1809 | 5% | 0.45 | 22 / 472 |
| ovary | 0% | 0 | 0 / 180 | 33% | 2.11 | 143 / 430 |
| thymus | 4% | 0.36 | 23 / 653 | 25% | 0.99 | 154 / 605 |
| kidney | 17% | 5.18 | 15 / 89 | 10% | 0.61 | 93 / 901 |
| uterus | 2% | 0.31 | 4 / 170 | 14% | 1.40 | 64 / 459 |
| pancreas | 2% | 0.42 | 7 / 328 | 11% | 0.21 | 20 / 178 |
| lung | 2% | 0.38 | 13 / 578 | 9% | 0.39 | 102 / 1155 |
| breast | 3% | 0.31 | 13 / 459 | 7% | 0.26 | 81 / 1118 |
| bladder | 0% | 0 | 0 / 21 | 10% | 0.72 | 49 / 504 |
| esophagus | 2% | 0.15 | 26 / 1445 | 5% | 0.49 | 10 / 183 |
| intestine | 0% | 0.02 | 2 / 966 | 3% | 0.10 | 18 / 527 |
| liver | 1% | 0.16 | 3 / 226 | 2% | 0.29 | 9 / 406 |
| prostate | 3% | 0.30 | 7 / 245 | 0% | 0 | 0 / 502 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.03 | 1 / 45 |
| stomach | 0% | 0 | 0 / 359 | 2% | 0.03 | 5 / 286 |
| blood vessel | 2% | 0.15 | 22 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 1% | 1.01 | 15 / 1204 | 0% | 0 | 0 / 0 |
| brain | 1% | 0.19 | 20 / 2642 | 0% | 0.00 | 1 / 705 |
| muscle | 1% | 0.15 | 7 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 0.07 | 8 / 929 | 0% | 0 | 0 / 0 |
| spleen | 1% | 0.06 | 2 / 241 | 0% | 0 | 0 / 0 |
| heart | 1% | 0.07 | 6 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0005829 | Cellular component | cytosol |
| GO_0045095 | Cellular component | keratin filament |
| GO_0005515 | Molecular function | protein binding |
| Gene name | KRTAP2-3 |
| Protein name | Keratin-associated protein 2-3 (High sulfur keratin-associated protein 2.4) (Keratin-associated protein 2.3) |
| Synonyms | KAP2.3 KRTAP2.3 |
| Description | FUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity). . |
| Accessions | ENST00000709598.1 P0C7H8 ENST00000570303.2 ENST00000391418.3 |