KRTAP11-1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KRTAP11-1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KRTAP11-1 at tissue level.

III. Associated gene sets

GO_0005829Cellular componentcytosol
GO_0045095Cellular componentkeratin filament
GO_0005198Molecular functionstructural molecule activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKRTAP11-1
Protein nameKeratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1)
Keratin-associated protein
SynonymsKRTAP11.1
KAP11.1
DescriptionFUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

FUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. .

AccessionsENST00000332378.6
Q3LI55
Q8IUC1