KRTAP10-6 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KRTAP10-6 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KRTAP10-6 at tissue level.

III. Associated gene sets

GO_0005829Cellular componentcytosol
GO_0045095Cellular componentkeratin filament
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKRTAP10-6
Protein nameKeratin-associated protein 10-6 (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6)
KRTAP10-6 protein
SynonymsKRTAP18.6
KRTAP18-6
KRTAP10.6
KAP10.6
KAP18-6
DescriptionFUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

FUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. .

AccessionsB9EIL2
P60371
ENST00000400368.1