Insufficient scRNA-seq data for expression of KRTAP1-5 at single-cell level.
Insufficient scRNA-seq data for expression of KRTAP1-5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 60% | 1934.24 | 1094 / 1809 | 1% | 1.72 | 6 / 472 |
| prostate | 22% | 6.35 | 55 / 245 | 5% | 0.09 | 26 / 502 |
| uterus | 15% | 6.50 | 25 / 170 | 5% | 0.80 | 24 / 459 |
| kidney | 18% | 5.71 | 16 / 89 | 1% | 0.02 | 11 / 901 |
| adipose | 17% | 13.33 | 208 / 1204 | 0% | 0 | 0 / 0 |
| bladder | 5% | 0.86 | 1 / 21 | 5% | 0.09 | 25 / 504 |
| breast | 7% | 1.35 | 31 / 459 | 1% | 0.02 | 6 / 1118 |
| blood vessel | 6% | 2.26 | 83 / 1335 | 0% | 0 | 0 / 0 |
| esophagus | 2% | 0.40 | 31 / 1445 | 2% | 0.09 | 3 / 183 |
| lung | 1% | 0.48 | 8 / 578 | 1% | 0.03 | 8 / 1155 |
| ovary | 1% | 0.14 | 2 / 180 | 1% | 0.01 | 3 / 430 |
| intestine | 1% | 0.35 | 10 / 966 | 1% | 0.06 | 4 / 527 |
| adrenal gland | 2% | 0.24 | 4 / 258 | 0% | 0 | 0 / 230 |
| peripheral blood | 1% | 0.23 | 13 / 929 | 0% | 0 | 0 / 0 |
| stomach | 1% | 0.08 | 2 / 359 | 1% | 0.01 | 2 / 286 |
| heart | 1% | 0.18 | 9 / 861 | 0% | 0 | 0 / 0 |
| muscle | 1% | 0.39 | 7 / 803 | 0% | 0 | 0 / 0 |
| thymus | 1% | 0.13 | 5 / 653 | 0% | 0 | 0 / 605 |
| brain | 0% | 0.08 | 11 / 2642 | 0% | 0.00 | 2 / 705 |
| pancreas | 0% | 0 | 0 / 328 | 1% | 0.01 | 1 / 178 |
| liver | 0% | 0.07 | 1 / 226 | 0% | 0 | 0 / 406 |
| spleen | 0% | 0.22 | 1 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0008150 | Biological process | biological_process |
| GO_0005575 | Cellular component | cellular_component |
| GO_0005829 | Cellular component | cytosol |
| GO_0045095 | Cellular component | keratin filament |
| GO_0005515 | Molecular function | protein binding |
| GO_0003674 | Molecular function | molecular_function |
| Gene name | KRTAP1-5 |
| Protein name | Keratin-associated protein 1-5 (High sulfur keratin-associated protein 1.5) (Keratin-associated protein 1.5) |
| Synonyms | KRTAP1.5 KAP1.5 |
| Description | FUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. |
| Accessions | ENST00000361883.6 ENST00000572212.1 Q9BYS1 |