KRTAP1-3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KRTAP1-3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KRTAP1-3 at tissue level.

III. Associated gene sets

GO_0008150Biological processbiological_process
GO_0005829Cellular componentcytosol
GO_0045095Cellular componentkeratin filament
GO_0030280Molecular functionstructural constituent of skin epidermis
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKRTAP1-3
Protein nameKeratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9)
SynonymsKRATP1.9
B2B
KAP1.9
KRTAP1.8
KAP1.2
KAP1.8
KAP1.3
DescriptionFUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

AccessionsQ8IUG1
ENST00000344363.7
ENST00000575715.2