KRTAP1-1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KRTAP1-1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KRTAP1-1 at tissue level.

III. Associated gene sets

GO_0008150Biological processbiological_process
GO_0005829Cellular componentcytosol
GO_0045095Cellular componentkeratin filament
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKRTAP1-1
Protein nameKeratin-associated protein 1-1 (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7)
SynonymsKAP1.7
KAP1.1
B2A
KRTAP1.1
KAP1.6
DescriptionFUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

AccessionsENST00000306271.5
Q07627
ENST00000573871.1