KNTC1 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	3 studies	20% ± 2%	Explore
transit amplifying cell	3 studies	45% ± 25%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of KNTC1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1097.45	1443 / 1445	100%	20.14	183 / 183
breast	100%	1266.11	459 / 459	99%	11.10	1107 / 1118
bladder	100%	941.81	21 / 21	99%	10.80	497 / 504
uterus	100%	1063.36	170 / 170	98%	17.15	452 / 459
lung	100%	1263.80	577 / 578	98%	11.20	1137 / 1155
intestine	100%	1380.26	965 / 966	97%	9.90	512 / 527
stomach	99%	838.23	357 / 359	98%	10.91	279 / 286
ovary	100%	1233.99	180 / 180	96%	8.00	414 / 430
skin	100%	1895.52	1809 / 1809	96%	10.27	453 / 472
pancreas	98%	523.88	321 / 328	94%	5.68	167 / 178
kidney	100%	835.06	89 / 89	89%	4.81	801 / 901
thymus	100%	906.10	651 / 653	84%	4.20	509 / 605
adrenal gland	100%	1033.01	258 / 258	66%	3.25	151 / 230
brain	81%	334.80	2137 / 2642	84%	5.14	595 / 705
prostate	100%	1131.76	245 / 245	64%	2.20	320 / 502
liver	92%	437.92	207 / 226	58%	3.59	235 / 406
adipose	100%	1120.72	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	14.77	29 / 29
spleen	100%	2465.02	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	19.23	45 / 45
ureter	0%	0	0 / 0	100%	6.95	1 / 1
blood vessel	99%	751.27	1325 / 1335	0%	0	0 / 0
heart	83%	364.28	712 / 861	0%	0	0 / 0
peripheral blood	77%	2113.05	716 / 929	0%	0	0 / 0
muscle	57%	179.39	461 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	46%	1.56	37 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0051988	Biological process	regulation of attachment of spindle microtubules to kinetochore
GO_0007096	Biological process	regulation of exit from mitosis
GO_0051301	Biological process	cell division
GO_0007094	Biological process	mitotic spindle assembly checkpoint signaling
GO_1903394	Biological process	protein localization to kinetochore involved in kinetochore assembly
GO_0000070	Biological process	mitotic sister chromatid segregation
GO_0065003	Biological process	protein-containing complex assembly
GO_1990423	Cellular component	RZZ complex
GO_0015629	Cellular component	actin cytoskeleton
GO_0005828	Cellular component	kinetochore microtubule
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0000922	Cellular component	spindle pole
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0031267	Molecular function	small GTPase binding
GO_0005515	Molecular function	protein binding

Gene name	KNTC1
Protein name	Kinetochore associated 1 Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod)
Synonyms	KIAA0166
Description	FUNCTION: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores . Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex. .
Accessions	ENST00000333479.12 [P50748-1] ENST00000450485.6 F5H5V0 ENST00000534995.1 H0YFL5 ENST00000423927.2 E7ES84 ENST00000436959.7 ENST00000546125.1 P50748 J3KQF2

KNTC1 report