KLK5 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KLK5 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KLK5 at tissue level.

III. Associated gene sets

GO_0002803Biological processpositive regulation of antibacterial peptide production
GO_0022617Biological processextracellular matrix disassembly
GO_0008544Biological processepidermis development
GO_0070268Biological processcornification
GO_0006508Biological processproteolysis
GO_0097186Biological processamelogenesis
GO_0045745Biological processpositive regulation of G protein-coupled receptor signaling pathway
GO_0005615Cellular componentextracellular space
GO_0030141Cellular componentsecretory granule
GO_0005829Cellular componentcytosol
GO_0005576Cellular componentextracellular region
GO_0097209Cellular componentepidermal lamellar body
GO_0008236Molecular functionserine-type peptidase activity
GO_0008233Molecular functionpeptidase activity
GO_0005515Molecular functionprotein binding
GO_0004252Molecular functionserine-type endopeptidase activity

IV. Literature review

[source]
Gene nameKLK5
Protein nameKallikrein related peptidase 5
Kallikrein 5 isoform 3 preproprotein (Kallikrein 5, isoform CRA_b)
Kallikrein-related peptidase 5 transcript variant 6
Kallikrein-5 (EC 3.4.21.-) (Kallikrein-like protein 2) (KLK-L2) (Stratum corneum tryptic enzyme)
Kallikrein-related peptidase 5 transcript variant 5
SynonymshCG_22933
SCTE
KLKL2
KLK-L2
UNQ570/PRO1132
DescriptionFUNCTION: May be involved in desquamation.

AccessionsM0QXX2
A0A2I2MP49
Q6S9W8
ENST00000593428.5
A0A2I2MP48
ENST00000391809.6
ENST00000594846.1
Q9Y337
ENST00000336334.8