KLK4 | OmnibusX

Name	Number of supported studies	Average coverage
luminal cell of prostate epithelium	4 studies	43% ± 8%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of KLK4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	19100.16	244 / 245	100%	1538.63	502 / 502
thymus	99%	243.54	644 / 653	23%	4.97	138 / 605
breast	59%	118.86	273 / 459	62%	6.19	688 / 1118
adrenal gland	76%	146.53	197 / 258	34%	21.38	79 / 230
intestine	57%	50.30	548 / 966	14%	0.92	75 / 527
uterus	48%	194.05	81 / 170	12%	2.71	55 / 459
skin	45%	18.97	814 / 1809	10%	1.08	45 / 472
kidney	24%	9.99	21 / 89	16%	21.55	142 / 901
bladder	14%	8.38	3 / 21	12%	1.25	62 / 504
lung	19%	6.83	108 / 578	6%	0.52	67 / 1155
pancreas	1%	0.55	4 / 328	19%	0.80	34 / 178
esophagus	7%	2.86	94 / 1445	11%	0.60	21 / 183
brain	16%	4.09	422 / 2642	1%	0.03	8 / 705
adipose	16%	7.93	197 / 1204	0%	0	0 / 0
peripheral blood	15%	10.99	141 / 929	0%	0	0 / 0
stomach	1%	0.15	3 / 359	12%	2.28	34 / 286
ovary	7%	4.20	12 / 180	4%	0.20	19 / 430
spleen	10%	2.20	25 / 241	0%	0	0 / 0
liver	0%	0.16	1 / 226	7%	2.50	30 / 406
lymph node	0%	0	0 / 0	7%	0.32	2 / 29
blood vessel	5%	7.22	64 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	4%	0.12	2 / 45
muscle	2%	0.72	16 / 803	0%	0	0 / 0
heart	1%	0.41	7 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0022617	Biological process	extracellular matrix disassembly
GO_0031214	Biological process	biomineral tissue development
GO_0006508	Biological process	proteolysis
GO_0097186	Biological process	amelogenesis
GO_0030141	Cellular component	secretory granule
GO_0005576	Cellular component	extracellular region
GO_0008236	Molecular function	serine-type peptidase activity
GO_0005515	Molecular function	protein binding
GO_0004252	Molecular function	serine-type endopeptidase activity
GO_0046872	Molecular function	metal ion binding

Gene name	KLK4
Protein name	Kallikrein-4 (EC 3.4.21.-) (Enamel matrix serine proteinase 1) (Kallikrein-like protein 1) (KLK-L1) (Prostase) (Serine protease 17) KLK4-KLKP1 fusion protein Kallikrein Kallikrein 4 splice variant Kallikrein related peptidase 4 Kallikrein-related peptidase 4 Kallikrein 4 (Prostase, enamel matrix, prostate), isoform CRA_a (Kallikrein B1) (Kallikrein related peptidase 4) Kallikrein 4 (EC 3.4.21.-) (Kallikrein related peptidase 4) KLK4 protein
Synonyms	KLNB1 hCG_1641510 PRSS17 PSTS EMSP1 fusion KLKP1
Description	FUNCTION: Has a major role in enamel formation . Required during the maturation stage of tooth development for clearance of enamel proteins and normal structural patterning of the crystalline matrix (By similarity). .
Accessions	ENST00000324041.6 ENST00000593885.1 ENST00000598305.5 Q9Y5K2 Q4VB17 Q4VB18 ENST00000431178.2 [Q9Y5K2-2] ENST00000602148.1 M0QYN5 Q96PT1 Q96PT0 Q5BQA0 A0A5B8NGJ8 B1GRN1 A0A0C4DFQ5

KLK4 report