KLK3 | OmnibusX

Name	Number of supported studies	Average coverage
luminal cell of prostate epithelium	4 studies	84% ± 4%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of KLK3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	426983.29	245 / 245	100%	14538.17	502 / 502
thymus	98%	106.58	643 / 653	9%	1.17	54 / 605
kidney	89%	50.38	79 / 89	10%	1.19	94 / 901
adrenal gland	75%	54.68	194 / 258	10%	7.81	23 / 230
intestine	70%	162.46	680 / 966	6%	0.56	32 / 527
breast	61%	755.93	278 / 459	5%	1.18	51 / 1118
uterus	59%	62.15	101 / 170	5%	1.50	22 / 459
pancreas	53%	35.82	173 / 328	11%	1.94	20 / 178
bladder	57%	40.33	12 / 21	5%	2.64	24 / 504
liver	49%	20.67	111 / 226	5%	0.76	21 / 406
ovary	49%	26.78	89 / 180	0%	0	0 / 430
stomach	48%	21.90	171 / 359	1%	0.30	4 / 286
skin	40%	28.23	730 / 1809	3%	0.84	15 / 472
esophagus	41%	25.07	599 / 1445	1%	0.07	2 / 183
spleen	41%	18.61	100 / 241	0%	0	0 / 0
lung	36%	18.61	209 / 578	1%	0.10	7 / 1155
heart	30%	19.79	259 / 861	0%	0	0 / 0
adipose	29%	35.11	355 / 1204	0%	0	0 / 0
blood vessel	29%	157.07	387 / 1335	0%	0	0 / 0
peripheral blood	28%	12.73	263 / 929	0%	0	0 / 0
brain	24%	11.77	634 / 2642	4%	0.57	28 / 705
muscle	24%	17.84	190 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	17%	2.53	5 / 29
eye	0%	0	0 / 0	6%	0.79	5 / 80
tonsil	0%	0	0 / 0	2%	0.09	1 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0002803	Biological process	positive regulation of antibacterial peptide production
GO_0016525	Biological process	negative regulation of angiogenesis
GO_0006508	Biological process	proteolysis
GO_0019538	Biological process	protein metabolic process
GO_0005615	Cellular component	extracellular space
GO_0030141	Cellular component	secretory granule
GO_0070062	Cellular component	extracellular exosome
GO_0032991	Cellular component	protein-containing complex
GO_0005576	Cellular component	extracellular region
GO_0005634	Cellular component	nucleus
GO_0016811	Molecular function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO_0008236	Molecular function	serine-type peptidase activity
GO_0004175	Molecular function	endopeptidase activity
GO_0005515	Molecular function	protein binding
GO_0004252	Molecular function	serine-type endopeptidase activity

Gene name	KLK3
Protein name	Kallikrein 3, (Prostate specific antigen), isoform CRA_e (Putative preproPSA-RP2) Kallikrein 3, (Prostate specific antigen), isoform CRA_a (Kallikrein related peptidase 3) Kallikrein 3, (Prostate specific antigen), isoform CRA_d (Kallikrein related peptidase 3) Kallikrein 3, (Prostate specific antigen), isoform CRA_f (Kallikrein related peptidase 3) Prostate specific antigen (Kallikrein A2) (cDNA, FLJ93384, Homo sapiens kallikrein 3, (prostate specific antigen) (KLK3),transcript variant 1, mRNA) Prostate-specific antigen (PSA) (EC 3.4.21.77) (Gamma-seminoprotein) (Seminin) (Kallikrein-3) (P-30 antigen) (Semenogelase) Prostate specific antigen Prostate specific antigen (Kallikrein related peptidase 3) (Prostate-specific antigen variant 1) (Prostate-specific antigen variant 2) Kallikrein related peptidase 3
Synonyms	APS hCG_22929 KLNA2
Description	FUNCTION: Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
Accessions	A0A0B4J1X3 ENST00000595392.5 Q546G3 ENST00000422986.6 M0R1F0 P07288 ENST00000597483.5 M0R1Z7 ENST00000598145.1 M0QZF9 Q8NCW4 ENST00000595952.5 [P07288-3] ENST00000326003.7 [P07288-1] Q7LBD2 ENST00000360617.7 [P07288-2] ENST00000596185.5 ENST00000601503.5 M0R294 ENST00000593997.5 [P07288-5] Q96A30 ENST00000597286.5 M0QX57

KLK3 report