KLHL9 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016567Biological processprotein ubiquitination
GO_0051301Biological processcell division
GO_0032465Biological processregulation of cytokinesis
GO_0030496Cellular componentmidbody
GO_0005829Cellular componentcytosol
GO_0031463Cellular componentCul3-RING ubiquitin ligase complex
GO_0004842Molecular functionubiquitin-protein transferase activity
GO_0097602Molecular functioncullin family protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKLHL9
Protein nameKelch-like 9 (Drosophila) (cDNA FLJ34396 fis, clone HCHON2000826, highly similar to Kelch-like protein 9)
Kelch-like protein 9
SynonymsKIAA1354
hCG_1647676
DescriptionFUNCTION: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. .

AccessionsENST00000359039.5
Q58EZ4
Q9P2J3