Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte precursor cell | 13 studies | 38% ± 16% | |
| GABAergic neuron | 9 studies | 41% ± 20% | |
| glutamatergic neuron | 9 studies | 43% ± 25% | |
| astrocyte | 9 studies | 27% ± 11% | |
| endothelial cell | 6 studies | 31% ± 13% | |
| interneuron | 6 studies | 42% ± 17% | |
| neuron | 5 studies | 37% ± 11% | |
| retina horizontal cell | 5 studies | 24% ± 6% | |
| cardiac muscle cell | 5 studies | 51% ± 12% | |
| granule cell | 4 studies | 22% ± 4% | |
| epithelial cell | 4 studies | 28% ± 3% | |
| retinal cone cell | 4 studies | 22% ± 4% | |
| fibroblast | 4 studies | 19% ± 5% | |
| oligodendrocyte | 4 studies | 25% ± 8% | |
| GABAergic interneuron | 3 studies | 26% ± 9% | |
| retinal ganglion cell | 3 studies | 24% ± 9% | |
| amacrine cell | 3 studies | 21% ± 1% | |
| ciliated cell | 3 studies | 21% ± 2% | |
| GABAergic amacrine cell | 3 studies | 23% ± 3% | |
| glycinergic amacrine cell | 3 studies | 21% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1365.22 | 1445 / 1445 | 100% | 15.55 | 183 / 183 |
| brain | 100% | 2062.76 | 2640 / 2642 | 100% | 34.73 | 705 / 705 |
| ovary | 100% | 1771.63 | 180 / 180 | 100% | 12.63 | 428 / 430 |
| breast | 100% | 1452.81 | 459 / 459 | 99% | 15.75 | 1111 / 1118 |
| prostate | 100% | 1238.93 | 244 / 245 | 100% | 17.65 | 500 / 502 |
| adrenal gland | 100% | 2682.10 | 258 / 258 | 99% | 15.10 | 228 / 230 |
| bladder | 100% | 1389.52 | 21 / 21 | 99% | 13.14 | 498 / 504 |
| lung | 99% | 1093.11 | 572 / 578 | 100% | 16.81 | 1153 / 1155 |
| thymus | 100% | 1166.91 | 651 / 653 | 99% | 12.33 | 599 / 605 |
| uterus | 100% | 1706.57 | 170 / 170 | 99% | 15.25 | 453 / 459 |
| kidney | 100% | 860.49 | 89 / 89 | 98% | 13.53 | 887 / 901 |
| intestine | 100% | 1356.13 | 966 / 966 | 98% | 9.97 | 518 / 527 |
| skin | 100% | 1768.54 | 1808 / 1809 | 97% | 18.39 | 460 / 472 |
| stomach | 99% | 890.93 | 354 / 359 | 99% | 10.26 | 282 / 286 |
| pancreas | 95% | 606.80 | 313 / 328 | 98% | 11.13 | 175 / 178 |
| liver | 83% | 407.08 | 188 / 226 | 88% | 6.30 | 358 / 406 |
| adipose | 100% | 1476.03 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1616.12 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1018.63 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 11.98 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.68 | 1 / 1 |
| muscle | 100% | 1066.02 | 802 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 4028.16 | 838 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 7.96 | 27 / 29 |
| eye | 0% | 0 | 0 / 0 | 85% | 7.66 | 68 / 80 |
| peripheral blood | 66% | 512.05 | 615 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0016567 | Biological process | protein ubiquitination |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0031463 | Cellular component | Cul3-RING ubiquitin ligase complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | KLHL7 |
| Protein name | Kelch like family member 7 Kelch-like protein 7 |
| Synonyms | |
| Description | FUNCTION: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination. . |
| Accessions | ENST00000410047.1 [Q8IXQ5-4] ENST00000409689.5 [Q8IXQ5-5] ENST00000521082.5 H7C259 ENST00000414163.1 E5RFN1 ENST00000322275.9 [Q8IXQ5-3] Q8IXQ5 ENST00000339077.10 [Q8IXQ5-1] |