KLHL41 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KLHL41 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KLHL41 at tissue level.

III. Associated gene sets

GO_0006941Biological processstriated muscle contraction
GO_0016567Biological processprotein ubiquitination
GO_2001014Biological processregulation of skeletal muscle cell differentiation
GO_0031269Biological processpseudopodium assembly
GO_2000291Biological processregulation of myoblast proliferation
GO_0030239Biological processmyofibril assembly
GO_0035914Biological processskeletal muscle cell differentiation
GO_0045661Biological processregulation of myoblast differentiation
GO_0001726Cellular componentruffle
GO_0005856Cellular componentcytoskeleton
GO_0005886Cellular componentplasma membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005654Cellular componentnucleoplasm
GO_0031463Cellular componentCul3-RING ubiquitin ligase complex
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0031143Cellular componentpseudopodium
GO_0033017Cellular componentsarcoplasmic reticulum membrane
GO_0031430Cellular componentM band
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKLHL41
Protein nameKelch-like protein 41 (Kel-like protein 23) (Kelch repeat and BTB domain-containing protein 10) (Kelch-related protein 1) (Sarcosin)
SynonymsKRP1
KBTBD10
DescriptionFUNCTION: Involved in skeletal muscle development and differentiation. Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. Required for pseudopod elongation in transformed cells. .

AccessionsO60662
ENST00000284669.2 [O60662-1]