Insufficient scRNA-seq data for expression of KLHL41 at single-cell level.
Insufficient scRNA-seq data for expression of KLHL41 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 69% | 960.21 | 170 / 245 | 38% | 7.63 | 192 / 502 |
muscle | 100% | 303792.32 | 803 / 803 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.42 | 1 / 1 |
heart | 98% | 5760.40 | 843 / 861 | 0% | 0 | 0 / 0 |
brain | 58% | 167.58 | 1525 / 2642 | 36% | 0.53 | 251 / 705 |
thymus | 72% | 271.70 | 473 / 653 | 17% | 0.73 | 101 / 605 |
bladder | 62% | 508.10 | 13 / 21 | 6% | 0.18 | 30 / 504 |
lung | 60% | 274.81 | 344 / 578 | 7% | 0.33 | 77 / 1155 |
uterus | 40% | 88.54 | 68 / 170 | 14% | 12.36 | 64 / 459 |
esophagus | 43% | 295.85 | 628 / 1445 | 5% | 0.08 | 10 / 183 |
eye | 0% | 0 | 0 / 0 | 46% | 1.08 | 37 / 80 |
breast | 21% | 179.44 | 97 / 459 | 24% | 0.80 | 263 / 1118 |
skin | 14% | 225.28 | 255 / 1809 | 30% | 1.41 | 140 / 472 |
ovary | 34% | 79.13 | 62 / 180 | 7% | 0.26 | 28 / 430 |
pancreas | 10% | 22.59 | 34 / 328 | 22% | 1.17 | 40 / 178 |
stomach | 28% | 89.73 | 99 / 359 | 5% | 0.78 | 15 / 286 |
intestine | 26% | 71.29 | 254 / 966 | 2% | 0.15 | 11 / 527 |
blood vessel | 28% | 242.78 | 369 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 22% | 6.74 | 10 / 45 |
adipose | 16% | 83.61 | 198 / 1204 | 0% | 0 | 0 / 0 |
spleen | 14% | 33.57 | 33 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 7% | 14.85 | 17 / 258 | 4% | 0.10 | 10 / 230 |
kidney | 7% | 12.38 | 6 / 89 | 4% | 0.07 | 32 / 901 |
peripheral blood | 10% | 76.63 | 90 / 929 | 0% | 0 | 0 / 0 |
liver | 7% | 21.53 | 15 / 226 | 2% | 0.07 | 9 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006941 | Biological process | striated muscle contraction |
GO_0016567 | Biological process | protein ubiquitination |
GO_2001014 | Biological process | regulation of skeletal muscle cell differentiation |
GO_0031269 | Biological process | pseudopodium assembly |
GO_2000291 | Biological process | regulation of myoblast proliferation |
GO_0030239 | Biological process | myofibril assembly |
GO_0035914 | Biological process | skeletal muscle cell differentiation |
GO_0045661 | Biological process | regulation of myoblast differentiation |
GO_0001726 | Cellular component | ruffle |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005886 | Cellular component | plasma membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005654 | Cellular component | nucleoplasm |
GO_0031463 | Cellular component | Cul3-RING ubiquitin ligase complex |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0031143 | Cellular component | pseudopodium |
GO_0033017 | Cellular component | sarcoplasmic reticulum membrane |
GO_0031430 | Cellular component | M band |
GO_0005515 | Molecular function | protein binding |
Gene name | KLHL41 |
Protein name | Kelch-like protein 41 (Kel-like protein 23) (Kelch repeat and BTB domain-containing protein 10) (Kelch-related protein 1) (Sarcosin) |
Synonyms | KRP1 KBTBD10 |
Description | FUNCTION: Involved in skeletal muscle development and differentiation. Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. Required for pseudopod elongation in transformed cells. . |
Accessions | O60662 ENST00000284669.2 [O60662-1] |