I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| CD16-positive, CD56-dim natural killer cell, human | 6 studies | 17% ± 2% | |
| gamma-delta T cell | 5 studies | 16% ± 1% | |
| natural killer cell | 4 studies | 20% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| CD16-positive, CD56-dim natural killer cell, human | 6 studies | 17% ± 2% | |
| gamma-delta T cell | 5 studies | 16% ± 1% | |
| natural killer cell | 4 studies | 20% ± 3% |
Insufficient scRNA-seq data for expression of KIR3DL2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 96% | 47.29 | 556 / 578 | 10% | 0.47 | 110 / 1155 |
| spleen | 100% | 170.87 | 241 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 82% | 419.88 | 765 / 929 | 0% | 0 | 0 / 0 |
| adipose | 60% | 9.88 | 721 / 1204 | 0% | 0 | 0 / 0 |
| breast | 49% | 6.80 | 223 / 459 | 8% | 0.18 | 91 / 1118 |
| liver | 52% | 7.42 | 117 / 226 | 1% | 0.02 | 3 / 406 |
| thymus | 43% | 6.19 | 282 / 653 | 7% | 0.14 | 44 / 605 |
| bladder | 43% | 3.14 | 9 / 21 | 6% | 0.24 | 29 / 504 |
| intestine | 39% | 7.66 | 374 / 966 | 7% | 0.12 | 35 / 527 |
| uterus | 31% | 2.83 | 52 / 170 | 13% | 0.69 | 61 / 459 |
| stomach | 26% | 3.01 | 95 / 359 | 12% | 0.21 | 34 / 286 |
| lymph node | 0% | 0 | 0 / 0 | 34% | 1.32 | 10 / 29 |
| kidney | 19% | 2.19 | 17 / 89 | 12% | 0.21 | 112 / 901 |
| tonsil | 0% | 0 | 0 / 0 | 31% | 0.91 | 14 / 45 |
| prostate | 27% | 3.20 | 65 / 245 | 2% | 0.03 | 10 / 502 |
| heart | 20% | 1.94 | 173 / 861 | 0% | 0 | 0 / 0 |
| esophagus | 14% | 1.34 | 196 / 1445 | 5% | 0.62 | 9 / 183 |
| blood vessel | 18% | 2.19 | 239 / 1335 | 0% | 0 | 0 / 0 |
| skin | 9% | 0.79 | 161 / 1809 | 9% | 0.18 | 42 / 472 |
| ovary | 13% | 1.40 | 23 / 180 | 2% | 0.04 | 9 / 430 |
| adrenal gland | 12% | 1.11 | 32 / 258 | 0% | 0 | 0 / 230 |
| muscle | 10% | 0.77 | 80 / 803 | 0% | 0 | 0 / 0 |
| brain | 6% | 0.51 | 163 / 2642 | 0% | 0 | 0 / 705 |
| pancreas | 3% | 0.24 | 10 / 328 | 1% | 0.04 | 2 / 178 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.04 | 2 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006968 | Biological process | cellular defense response |
| GO_0002764 | Biological process | immune response-regulating signaling pathway |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0023029 | Molecular function | MHC class Ib protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | KIR3DL2 |
| Protein name | Killer cell immunoglobulin-like receptor 3DL2 KIR3DL2 protein (Killer cell immunoglobulin-like receptor 3DL2) Killer cell immunoglobulin-like receptor 3DL2 (Truncated KIR3DL2) Killer cell immunoglobulin-like receptor 2DL2 Killer-cell immunoglobulin-like receptor KIR3DL2 (Killer-cell immunoglobulin-like receptor 3DL2) Killer-cell immunoglobulin-like receptor 3DL2 KIR3DL2 (Killer cell immunoglobulin-like receptor) (Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 2) Killer cell immunoglobulin-like receptor 3DL2 (Natural killer cell inhibitory receptor) KIR3DL2 protein (Killer cell immunoglobulin-like receptor 3DL2) (Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 2) KIR antigen 3DL2 KIR3DL2 KIR3DL2 (Killer cell immunoglobulin-like receptor) Killer cell immunoglobulin-like receptor (Killer-cell immunoglobulin-like receptor 3DL2) KIR3DL2 protein Killer cell immunoglobulin-like receptor 3DL2 (CD158 antigen-like family member K) (Natural killer-associated transcript 4) (NKAT-4) (p70 natural killer cell receptor clone CL-5) (p70 NK receptor CL-5) (CD antigen CD158k) Natural killer cell inhibitory receptor KIR3DL2 (Killer cell immunoglobulin-like receptor 3DL2) Killer cell immunoglobulin-like receptor KIR3DL2 (Killer cell immunoglobulin-like receptor 3DL2) (Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 2) (Natural killer cell inhibitory receptor) KIR3DL2 (Killer-cell immunoglobulin-like receptor) Inhibitory NK receptor (KIR3DL2) (Killer cell immunoglobulin-like receptor) 3DL2 (KIR3DL2 protein) (Killer cell immunoglobulin-like receptor) (Killer cell immunoglobulin-like receptor 3DL2) (Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 2) |
| Synonyms | NKAT4 kir3d CD158K 3DL2 KIR-3DL2 |
| Description | FUNCTION: Receptor on natural killer (NK) cells and T cells for MHC class I molecules . Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions . Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity . . |
| Accessions | Q32WD1 ENST00000612166.1 ENST00000613586.1 A0A0G2JMW7 A0A0U5FLC8 A0A0U5FL96 ENST00000617481.1 [P43630-2] A0A376A965 ENST00000639529.1 ENST00000616505.1 A0A6G6CYU7 A7YL09 ENST00000617666.4 E4W3U7 A0A0U1WN54 A0A0U1V1F4 A0A0U5GHD6 ENST00000620280.1 A0A0U5FLD8 A0A110BIQ8 ENST00000615147.4 ENST00000639511.1 A0A0G2JM59 A0A376A8V5 A0A110BGW5 A7YL13 ENST00000616626.1 A0A0U5FLS4 A0A0U5FNF5 ENST00000610507.1 A0A0G2JLU7 ENST00000621701.4 A0A0G2JLP2 A0A0G2JNN5 ENST00000618616.4 Q8NHI4 A0A7D5BV11 ENST00000614753.4 Q8NHL2 A0A5J6VMA2 A0A0U1WN28 A0A110BGN2 ENST00000640567.1 A0A223PQI2 ENST00000621155.4 A0A0G2JLM7 ENST00000610914.1 A0A0U1WNF1 ENST00000617957.4 [P43630-1] ENST00000270442.5 [P43630-2] A0A7D5BT33 A0A376A939 ENST00000640913.1 A0A0G2JNA1 ENST00000622024.4 ENST00000638168.1 A0A5J6VML4 ENST00000616438.4 E7BWR6 A0A0U1WNF4 ENST00000617398.4 ENST00000620817.4 [P43630-1] ENST00000622784.1 ENST00000620485.4 ENST00000639934.1 A0A0U1WN22 A0A7D5C6G1 ENST00000620550.4 A0A191URK3 A0A7D4XZ80 E4W3W0 A0A0U1WN38 A0A0U1WNF2 A0A0U1V1F2 E7BWR2 ENST00000613029.1 A0A0G2JM36 A0A0U5FT04 A0A223PQH3 A7YL11 E4W3V0 A0A0G2JN45 A0A0U4YTB3 E4W3U5 ENST00000618273.1 [P43630-2] A0A0G2JMA3 ENST00000617354.4 [P43630-1] A0A110BHB9 ENST00000617195.1 A0A110BGM1 A0A0G2JMI1 ENST00000615712.1 K7R1T8 A0A110BIQ9 A0A0U5FM20 A0A7D4XVD2 E4W3V8 ENST00000611872.1 E4W3U8 ENST00000611628.4 A0A0U1WNF6 ENST00000618475.1 A0A376A8T7 ENST00000610587.4 ENST00000615608.1 Q8NHK6 ENST00000613612.4 E4W3V3 ENST00000672168.1 Q8NHI5 ENST00000616961.1 ENST00000612634.1 ENST00000612483.1 A0A110BIP9 Q8NHL1 ENST00000612733.1 ENST00000612138.1 [P43630-2] A0A0U5GHC2 A0A0U4YTC8 A0A0G2JP59 ENST00000622574.1 A0A2R4FYM5 ENST00000620501.4 E7BWR7 ENST00000616854.1 ENST00000611859.1 [P43630-2] E7BWR5 ENST00000326321.7 [P43630-1] ENST00000672620.1 A0A0U1WN50 A0A1W2PP69 A0A0U1V1E6 P43630 A0A0U1WN45 A0A0G2JPL0 ENST00000638665.1 A0A0G2JP93 A0A120N654 A0A0U5FL38 A0A110BHC2 A0A120N5Z5 ENST00000619026.1 A0A0U1V1E4 Q32WD2 A0A120N617 E4W3V2 A0A0U5BZT5 ENST00000615308.4 ENST00000622579.1 [P43630-2] E4W3U3 E7BWR3 A0A0U1WNF3 ENST00000638389.1 A0A7D5BT22 A0A0U1WNF7 ENST00000640359.1 A0A0U1WN23 ENST00000673404.1 A0A0G2JLZ4 ENST00000610296.4 A0A0U5BZX3 A0A110BGU4 A0A0U5C0C5 A0A142DV42 A0A2I2JL18 Q6H2F6 ENST00000613109.1 A0A0U1V1E8 ENST00000615318.1 ENST00000622249.4 A0A0U1WN35 A0A7D4XV53 A7YL10 ENST00000672518.1 E7BWR4 Q9BQU0 E4W3V9 E4W3U6 A0A0G2JLX7 ENST00000640534.1 ENST00000615208.4 A0A120N5Z6 E4W3V6 A0A0G2JMS0 ENST00000619683.4 ENST00000617684.1 E4W3V1 A0A0U5FLQ7 A7YL12 E4W3U4 A0A7D5BW90 ENST00000613891.4 Q6QWD4 Q8NHI6 ENST00000673301.1 ENST00000618237.4 E4W3W1 ENST00000612018.1 Q6QWD5 ENST00000613610.4 K7R1S8 ENST00000673143.1 A0A0G2JPA6 A0A0U1WN03 A0A0G2JP67 A0A110BIP7 A7YL14 Q32WD0 ENST00000611608.4 [P43630-1] E4W3V4 E4W3V7 A0A0U1WNF9 A0A1W2PPV3 E4W3V5 ENST00000622453.4 [P43630-1] A0A0G2JPQ5 A0A0U1WNF5 |
