KIF4B report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KIF4B at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KIF4B at tissue level.

III. Associated gene sets

GO_0051231Biological processspindle elongation
GO_0051256Biological processmitotic spindle midzone assembly
GO_0000281Biological processmitotic cytokinesis
GO_0007018Biological processmicrotubule-based movement
GO_0007052Biological processmitotic spindle organization
GO_0016363Cellular componentnuclear matrix
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005875Cellular componentmicrotubule associated complex
GO_0005874Cellular componentmicrotubule
GO_0003677Molecular functionDNA binding
GO_0051536Molecular functioniron-sulfur cluster binding
GO_0003777Molecular functionmicrotubule motor activity
GO_0008017Molecular functionmicrotubule binding
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameKIF4B
Protein nameChromosome-associated kinesin KIF4B (Chromokinesin-B)
Synonyms
DescriptionFUNCTION: Iron-sulfur (Fe-S) cluster binding motor protein that has a role in chromosome segregation during mitosis (By similarity). Translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis (By similarity). May play a role in mitotic chromosomal positioning and bipolar spindle stabilization (By similarity). .

AccessionsENST00000435029.6
Q2VIQ3