KIF2C | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of KIF2C at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	96%	1222.92	1732 / 1809	94%	32.77	444 / 472
intestine	84%	305.52	807 / 966	96%	32.07	504 / 527
uterus	79%	110.31	134 / 170	97%	60.35	447 / 459
esophagus	75%	369.01	1086 / 1445	98%	36.58	180 / 183
lung	84%	181.07	485 / 578	85%	27.47	985 / 1155
stomach	68%	196.58	243 / 359	96%	30.22	274 / 286
bladder	67%	99.81	14 / 21	95%	38.50	479 / 504
ovary	60%	77.11	108 / 180	96%	30.25	411 / 430
breast	57%	77.51	262 / 459	85%	25.50	946 / 1118
thymus	93%	136.92	606 / 653	20%	8.79	120 / 605
lymph node	0%	0	0 / 0	100%	58.67	29 / 29
spleen	100%	503.18	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	67.16	45 / 45
ureter	0%	0	0 / 0	100%	23.32	1 / 1
prostate	80%	111.48	196 / 245	9%	1.18	46 / 502
pancreas	10%	11.80	34 / 328	69%	13.12	123 / 178
peripheral blood	72%	1479.84	667 / 929	0%	0	0 / 0
adrenal gland	61%	90.04	157 / 258	10%	2.54	22 / 230
blood vessel	70%	108.65	928 / 1335	0%	0	0 / 0
brain	28%	26.55	734 / 2642	41%	10.91	291 / 705
liver	19%	38.23	42 / 226	39%	7.32	158 / 406
kidney	40%	75.17	36 / 89	10%	1.80	94 / 901
adipose	48%	71.27	576 / 1204	0%	0	0 / 0
heart	46%	52.00	398 / 861	0%	0	0 / 0
muscle	8%	9.27	62 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	8%	0.83	6 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007019	Biological process	microtubule depolymerization
GO_0030951	Biological process	establishment or maintenance of microtubule cytoskeleton polarity
GO_0051310	Biological process	metaphase chromosome alignment
GO_0051315	Biological process	attachment of mitotic spindle microtubules to kinetochore
GO_0051301	Biological process	cell division
GO_0051983	Biological process	regulation of chromosome segregation
GO_0007018	Biological process	microtubule-based movement
GO_0007080	Biological process	mitotic metaphase chromosome alignment
GO_0000775	Cellular component	chromosome, centromeric region
GO_0005874	Cellular component	microtubule
GO_0016020	Cellular component	membrane
GO_0005813	Cellular component	centrosome
GO_0000776	Cellular component	kinetochore
GO_0035371	Cellular component	microtubule plus-end
GO_0005871	Cellular component	kinesin complex
GO_0005829	Cellular component	cytosol
GO_0015630	Cellular component	microtubule cytoskeleton
GO_0005881	Cellular component	cytoplasmic microtubule
GO_0005819	Cellular component	spindle
GO_0005634	Cellular component	nucleus
GO_0051010	Molecular function	microtubule plus-end binding
GO_0003777	Molecular function	microtubule motor activity
GO_0008017	Molecular function	microtubule binding
GO_0005524	Molecular function	ATP binding
GO_0019237	Molecular function	centromeric DNA binding
GO_0005515	Molecular function	protein binding
GO_0016887	Molecular function	ATP hydrolysis activity

Gene name	KIF2C
Protein name	Kinesin-like protein KIF2C (Kinesin-like protein 6) (Mitotic centromere-associated kinesin) (MCAK) Mitotic centromere-associated kinesin
Synonyms	KNSL6
Description	FUNCTION: In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells . Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis . Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment . .
Accessions	Q5JR91 Q99661 ENST00000455186.5 Q5JR89 ENST00000452259.5 ENST00000423289.1 ENST00000372224.9 [Q99661-1] ENST00000372217.5 [Q99661-2] H0Y5Z9

KIF2C report