KIF18A report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KIF18A at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KIF18A at tissue level.

III. Associated gene sets

GO_0007019Biological processmicrotubule depolymerization
GO_0000070Biological processmitotic sister chromatid segregation
GO_0071392Biological processcellular response to estradiol stimulus
GO_0072520Biological processseminiferous tubule development
GO_0007018Biological processmicrotubule-based movement
GO_0015031Biological processprotein transport
GO_0070507Biological processregulation of microtubule cytoskeleton organization
GO_0007080Biological processmitotic metaphase chromosome alignment
GO_0007140Biological processmale meiotic nuclear division
GO_0001726Cellular componentruffle
GO_0005813Cellular componentcentrosome
GO_0000776Cellular componentkinetochore
GO_0005871Cellular componentkinesin complex
GO_1990023Cellular componentmitotic spindle midzone
GO_0061673Cellular componentmitotic spindle astral microtubule
GO_0005828Cellular componentkinetochore microtubule
GO_0005829Cellular componentcytosol
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0005737Cellular componentcytoplasm
GO_0005901Cellular componentcaveola
GO_0005634Cellular componentnucleus
GO_0008574Molecular functionplus-end-directed microtubule motor activity
GO_0051010Molecular functionmicrotubule plus-end binding
GO_0070463Molecular functiontubulin-dependent ATPase activity
GO_0008017Molecular functionmicrotubule binding
GO_0005524Molecular functionATP binding
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding
GO_0016887Molecular functionATP hydrolysis activity

IV. Literature review

[source]
Gene nameKIF18A
Protein nameKinesin-like protein KIF18A (Marrow stromal KIF18A) (MS-KIF18A)
Kinesin-like protein
SynonymsOK/SW-cl.108
DescriptionFUNCTION: Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression. .

AccessionsQ8NI77
Q4G194
ENST00000263181.7