Insufficient scRNA-seq data for expression of KIF18A at single-cell level.
Insufficient scRNA-seq data for expression of KIF18A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 99% | 107.81 | 574 / 578 | 92% | 8.14 | 1057 / 1155 |
| skin | 98% | 418.20 | 1775 / 1809 | 82% | 6.67 | 389 / 472 |
| thymus | 100% | 123.19 | 652 / 653 | 77% | 3.85 | 468 / 605 |
| intestine | 77% | 81.61 | 741 / 966 | 94% | 7.80 | 495 / 527 |
| breast | 75% | 35.63 | 346 / 459 | 89% | 7.40 | 995 / 1118 |
| uterus | 68% | 26.92 | 116 / 170 | 95% | 10.71 | 437 / 459 |
| ovary | 66% | 31.34 | 118 / 180 | 96% | 8.20 | 413 / 430 |
| stomach | 60% | 50.08 | 215 / 359 | 95% | 8.52 | 272 / 286 |
| esophagus | 54% | 88.11 | 778 / 1445 | 99% | 14.15 | 182 / 183 |
| bladder | 62% | 22.38 | 13 / 21 | 88% | 7.28 | 445 / 504 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 10.63 | 29 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 12.94 | 45 / 45 |
| spleen | 100% | 122.53 | 240 / 241 | 0% | 0 | 0 / 0 |
| kidney | 65% | 32.98 | 58 / 89 | 25% | 0.98 | 226 / 901 |
| pancreas | 29% | 8.91 | 96 / 328 | 58% | 2.77 | 104 / 178 |
| prostate | 72% | 30.07 | 176 / 245 | 8% | 0.25 | 40 / 502 |
| adipose | 76% | 33.72 | 913 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 52% | 20.91 | 134 / 258 | 20% | 1.00 | 46 / 230 |
| blood vessel | 68% | 38.76 | 904 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 64% | 408.58 | 599 / 929 | 0% | 0 | 0 / 0 |
| brain | 22% | 7.40 | 593 / 2642 | 38% | 2.28 | 265 / 705 |
| liver | 15% | 9.55 | 34 / 226 | 35% | 1.73 | 141 / 406 |
| muscle | 42% | 15.45 | 341 / 803 | 0% | 0 | 0 / 0 |
| heart | 17% | 5.64 | 147 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.07 | 2 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007019 | Biological process | microtubule depolymerization |
| GO_0000070 | Biological process | mitotic sister chromatid segregation |
| GO_0071392 | Biological process | cellular response to estradiol stimulus |
| GO_0072520 | Biological process | seminiferous tubule development |
| GO_0007018 | Biological process | microtubule-based movement |
| GO_0015031 | Biological process | protein transport |
| GO_0070507 | Biological process | regulation of microtubule cytoskeleton organization |
| GO_0007080 | Biological process | mitotic metaphase chromosome alignment |
| GO_0007140 | Biological process | male meiotic nuclear division |
| GO_0001726 | Cellular component | ruffle |
| GO_0005813 | Cellular component | centrosome |
| GO_0000776 | Cellular component | kinetochore |
| GO_0005871 | Cellular component | kinesin complex |
| GO_1990023 | Cellular component | mitotic spindle midzone |
| GO_0061673 | Cellular component | mitotic spindle astral microtubule |
| GO_0005828 | Cellular component | kinetochore microtubule |
| GO_0005829 | Cellular component | cytosol |
| GO_0015630 | Cellular component | microtubule cytoskeleton |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005901 | Cellular component | caveola |
| GO_0005634 | Cellular component | nucleus |
| GO_0008574 | Molecular function | plus-end-directed microtubule motor activity |
| GO_0051010 | Molecular function | microtubule plus-end binding |
| GO_0070463 | Molecular function | tubulin-dependent ATPase activity |
| GO_0008017 | Molecular function | microtubule binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003779 | Molecular function | actin binding |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| Gene name | KIF18A |
| Protein name | Kinesin-like protein KIF18A (Marrow stromal KIF18A) (MS-KIF18A) Kinesin-like protein |
| Synonyms | OK/SW-cl.108 |
| Description | FUNCTION: Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression. . |
| Accessions | Q8NI77 Q4G194 ENST00000263181.7 |