I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 26% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 26% ± 8% |
Insufficient scRNA-seq data for expression of KDF1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 730.74 | 328 / 328 | 99% | 31.23 | 176 / 178 |
| thymus | 100% | 897.53 | 651 / 653 | 99% | 43.23 | 599 / 605 |
| prostate | 88% | 621.24 | 216 / 245 | 99% | 42.97 | 499 / 502 |
| lung | 77% | 323.03 | 447 / 578 | 99% | 39.11 | 1139 / 1155 |
| stomach | 75% | 620.38 | 270 / 359 | 97% | 36.07 | 277 / 286 |
| breast | 58% | 418.77 | 268 / 459 | 99% | 44.61 | 1105 / 1118 |
| kidney | 100% | 683.70 | 89 / 89 | 51% | 10.05 | 457 / 901 |
| intestine | 45% | 400.55 | 432 / 966 | 98% | 42.20 | 517 / 527 |
| bladder | 43% | 259.86 | 9 / 21 | 96% | 49.41 | 483 / 504 |
| esophagus | 39% | 534.18 | 558 / 1445 | 99% | 40.77 | 181 / 183 |
| liver | 73% | 171.66 | 164 / 226 | 39% | 6.77 | 157 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 53.37 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 55.93 | 1 / 1 |
| ovary | 0% | 0 | 0 / 180 | 98% | 45.74 | 423 / 430 |
| uterus | 6% | 24.86 | 11 / 170 | 88% | 48.02 | 403 / 459 |
| skin | 74% | 946.33 | 1341 / 1809 | 4% | 0.66 | 17 / 472 |
| adrenal gland | 26% | 45.16 | 67 / 258 | 3% | 1.08 | 7 / 230 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 1.27 | 3 / 29 |
| brain | 10% | 16.90 | 257 / 2642 | 0% | 0 | 0 / 705 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.29 | 2 / 80 |
| spleen | 2% | 3.69 | 6 / 241 | 0% | 0 | 0 / 0 |
| adipose | 1% | 3.06 | 11 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.77 | 3 / 929 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.34 | 2 / 803 | 0% | 0 | 0 / 0 |
| heart | 0% | 0.32 | 2 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.54 | 2 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0010482 | Biological process | regulation of epidermal cell division |
| GO_0060887 | Biological process | limb epidermis development |
| GO_0048589 | Biological process | developmental growth |
| GO_0045606 | Biological process | positive regulation of epidermal cell differentiation |
| GO_2000647 | Biological process | negative regulation of stem cell proliferation |
| GO_0072089 | Biological process | stem cell proliferation |
| GO_0061436 | Biological process | establishment of skin barrier |
| GO_0043616 | Biological process | keratinocyte proliferation |
| GO_0016331 | Biological process | morphogenesis of embryonic epithelium |
| GO_0010839 | Biological process | negative regulation of keratinocyte proliferation |
| GO_0003334 | Biological process | keratinocyte development |
| GO_0030054 | Cellular component | cell junction |
| GO_0005938 | Cellular component | cell cortex |
| GO_0070161 | Cellular component | anchoring junction |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0031252 | Cellular component | cell leading edge |
| GO_0005515 | Molecular function | protein binding |
| Gene name | KDF1 |
| Protein name | Keratinocyte differentiation factor 1 |
| Synonyms | C1orf172 |
| Description | FUNCTION: Plays a role in the regulation of the epidermis formation during early development. Required both as an inhibitor of basal cell proliferation and a promoter of differentiation of basal progenitor cell progeny (By similarity). . |
| Accessions | Q8NAX2 ENST00000320567.6 |
