KCTD10 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	6 studies	23% ± 5%	Explore
epithelial cell	4 studies	21% ± 4%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of KCTD10 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	7988.63	1445 / 1445	100%	23.24	183 / 183
ovary	100%	3798.17	180 / 180	100%	17.92	430 / 430
uterus	100%	8100.28	170 / 170	100%	24.64	459 / 459
thymus	100%	7796.39	653 / 653	100%	38.83	604 / 605
breast	100%	7399.18	459 / 459	100%	29.89	1116 / 1118
intestine	100%	7507.28	966 / 966	100%	24.78	526 / 527
bladder	100%	8485.05	21 / 21	100%	23.57	503 / 504
lung	100%	7064.32	577 / 578	100%	25.05	1154 / 1155
skin	100%	7172.75	1809 / 1809	100%	26.73	470 / 472
prostate	100%	6669.71	244 / 245	100%	28.11	501 / 502
kidney	100%	4420.38	89 / 89	99%	28.36	892 / 901
adrenal gland	100%	4751.81	258 / 258	98%	27.39	225 / 230
brain	96%	2551.28	2542 / 2642	100%	17.88	704 / 705
stomach	96%	4634.96	346 / 359	100%	23.54	285 / 286
pancreas	46%	820.22	151 / 328	98%	24.90	175 / 178
liver	38%	668.47	87 / 226	76%	8.59	309 / 406
adipose	100%	8042.60	1204 / 1204	0%	0	0 / 0
blood vessel	100%	17141.76	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	19.82	29 / 29
spleen	100%	4452.93	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	22.97	45 / 45
ureter	0%	0	0 / 0	100%	17.35	1 / 1
heart	97%	3244.30	832 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	96%	13.76	77 / 80
muscle	54%	982.08	430 / 803	0%	0	0 / 0
peripheral blood	52%	1591.27	486 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0035024	Biological process	negative regulation of Rho protein signal transduction
GO_0051260	Biological process	protein homooligomerization
GO_0016567	Biological process	protein ubiquitination
GO_0006511	Biological process	ubiquitin-dependent protein catabolic process
GO_0043161	Biological process	proteasome-mediated ubiquitin-dependent protein catabolic process
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0031463	Cellular component	Cul3-RING ubiquitin ligase complex
GO_0005112	Molecular function	Notch binding
GO_0004842	Molecular function	ubiquitin-protein transferase activity
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

Gene name	KCTD10
Protein name	Potassium channel tetramerisation domain containing 10, isoform CRA_a (Potassium channel tetramerization domain containing 10) (cDNA FLJ41739 fis, clone HSYRA2002590, highly similar to BTB/POZ domain-containing protein KCTD10) Alternative protein KCTD10 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (hBACURD3) (BTB/POZ domain-containing protein KCTD10) (Potassium channel tetramerization domain-containing protein 10) Potassium channel tetramerization domain containing 10
Synonyms	MSTP028 ULR061 hCG_40324
Description	FUNCTION: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(BACURD3) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome (By similarity). .
Accessions	Q9H3F6 F5GWK6 ENST00000535546.5 ENST00000537165.5 ENST00000542262.5 L8E9A8 ENST00000541077.1 ENST00000540089.5 ENST00000228495.11 [Q9H3F6-1] ENST00000540411.5 ENST00000540355.5 F5H497 F5GWA4 B3KVY5 S4R3L9 F8W8I7 S4R3Y7 F5GY15 ENST00000440541.6 ENST00000542954.5 F5H268 ENST00000542858.1 F5H6V0

KCTD10 report