KCNQ5 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	11 studies	74% ± 25%	Explore
GABAergic neuron	10 studies	55% ± 23%	Explore
microglial cell	7 studies	28% ± 18%	Explore
neuron	6 studies	34% ± 17%	Explore
interneuron	6 studies	47% ± 30%	Explore
oligodendrocyte precursor cell	5 studies	21% ± 5%	Explore
endothelial cell	5 studies	38% ± 17%	Explore
B cell	5 studies	30% ± 14%	Explore
astrocyte	4 studies	35% ± 26%	Explore
natural killer cell	4 studies	30% ± 5%	Explore
GABAergic interneuron	3 studies	67% ± 7%	Explore
oligodendrocyte	3 studies	41% ± 24%	Explore

Name	Number of supported studies	Average coverage
brain	13 studies	45% ± 27%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	92%	599.96	599 / 653	83%	4.42	503 / 605
brain	69%	2101.43	1812 / 2642	89%	8.38	628 / 705
muscle	100%	3452.53	800 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	99%	15.13	79 / 80
lymph node	0%	0	0 / 0	79%	2.74	23 / 29
skin	7%	24.68	133 / 1809	69%	4.94	326 / 472
blood vessel	73%	343.83	981 / 1335	0%	0	0 / 0
adrenal gland	7%	28.57	17 / 258	64%	8.93	147 / 230
prostate	43%	128.24	106 / 245	26%	0.44	131 / 502
bladder	52%	214.24	11 / 21	12%	0.47	62 / 504
esophagus	21%	60.14	306 / 1445	39%	1.62	71 / 183
spleen	57%	161.99	138 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	56%	1.97	25 / 45
lung	1%	2.28	6 / 578	52%	2.19	601 / 1155
breast	3%	7.52	12 / 459	41%	1.93	461 / 1118
intestine	23%	72.93	221 / 966	4%	0.09	21 / 527
ovary	1%	2.43	2 / 180	26%	0.92	110 / 430
peripheral blood	24%	526.25	222 / 929	0%	0	0 / 0
uterus	2%	7.05	3 / 170	22%	0.70	101 / 459
stomach	11%	35.10	39 / 359	5%	0.17	14 / 286
pancreas	0%	0	0 / 328	11%	0.27	20 / 178
kidney	0%	0	0 / 89	7%	0.17	67 / 901
liver	0%	0	0 / 226	2%	0.06	9 / 406
heart	1%	1.98	7 / 861	0%	0	0 / 0
adipose	0%	0.15	1 / 1204	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0071805	Biological process	potassium ion transmembrane transport
GO_0030118	Cellular component	clathrin coat
GO_0005886	Cellular component	plasma membrane
GO_0008076	Cellular component	voltage-gated potassium channel complex
GO_0005249	Molecular function	voltage-gated potassium channel activity
GO_0005515	Molecular function	protein binding

Gene name	KCNQ5
Protein name	Potassium voltage-gated channel subfamily Q member 5 Potassium voltage-gated channel subfamily KQT member 5 (KQT-like 5) (Potassium channel subunit alpha KvLQT5) (Voltage-gated potassium channel subunit Kv7.5)
Synonyms
Description	FUNCTION: Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. Therefore, it is important in the regulation of neuronal excitability. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current. Insensitive to tetraethylammonium, but inhibited by barium, linopirdine and XE991. Activated by niflumic acid and the anticonvulsant retigabine. As the native M-channel, the potassium channel composed of KCNQ3 and KCNQ5 is also suppressed by activation of the muscarinic acetylcholine receptor CHRM1. .
Accessions	H0Y3Z0 A6PVT8 ENST00000628967.2 [Q9NR82-5] ENST00000342056.6 [Q9NR82-6] A6PVT7 ENST00000629977.2 [Q9NR82-2] F8WEA4 ENST00000355194.9 ENST00000427928.1 ENST00000370398.6 [Q9NR82-1] ENST00000441538.1 ENST00000370392.5 [Q9NR82-4] Q9NR82 ENST00000443915.1

KCNQ5 report