KCNN1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KCNN1 at tissue level.

III. Associated gene sets

GO_0006813Biological processpotassium ion transport
GO_0007268Biological processchemical synaptic transmission
GO_0071805Biological processpotassium ion transmembrane transport
GO_0045202Cellular componentsynapse
GO_0043025Cellular componentneuronal cell body
GO_0005886Cellular componentplasma membrane
GO_0008076Cellular componentvoltage-gated potassium channel complex
GO_0043005Cellular componentneuron projection
GO_0016286Molecular functionsmall conductance calcium-activated potassium channel activity
GO_0015269Molecular functioncalcium-activated potassium channel activity
GO_0005516Molecular functioncalmodulin binding
GO_0005242Molecular functioninward rectifier potassium channel activity

IV. Literature review

[source]
Gene nameKCNN1
Protein namePotassium calcium-activated channel subfamily N member 1
Small conductance calcium-activated potassium channel protein 1 (SK1) (SKCa 1) (SKCa1) (KCa2.1)
Potassium calcium-activated channel subfamily N member 1 (Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1, isoform CRA_b)
SynonymshCG_36878
SK
DescriptionFUNCTION: Forms a voltage-independent potassium channel activated by intracellular calcium . Activation is followed by membrane hyperpolarization (By similarity). Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization (By similarity). .

AccessionsENST00000684775.1 [Q92952-1]
ENST00000684725.1
ENST00000682733.1
A0A087X2E7
A0A804HIJ6
ENST00000683588.1
ENST00000682726.1
A0A804HIW7
A0A804HK94
ENST00000609922.2
V9GYV2
A0A804HIF9
ENST00000683930.1
Q92952
ENST00000682421.1
ENST00000615435.2
ENST00000222249.13 [Q92952-1]