Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 4 studies | 25% ± 8% |
Insufficient scRNA-seq data for expression of KCNN1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 99% | 3698.14 | 2604 / 2642 | 97% | 14.39 | 687 / 705 |
ovary | 53% | 166.31 | 95 / 180 | 50% | 2.76 | 215 / 430 |
eye | 0% | 0 | 0 / 0 | 60% | 3.45 | 48 / 80 |
kidney | 1% | 1.80 | 1 / 89 | 43% | 2.42 | 386 / 901 |
uterus | 14% | 35.44 | 24 / 170 | 21% | 1.59 | 97 / 459 |
skin | 0% | 0 | 0 / 1809 | 29% | 1.36 | 139 / 472 |
adrenal gland | 0% | 0.71 | 1 / 258 | 27% | 2.09 | 63 / 230 |
lymph node | 0% | 0 | 0 / 0 | 17% | 0.52 | 5 / 29 |
prostate | 11% | 21.72 | 28 / 245 | 5% | 0.10 | 25 / 502 |
lung | 0% | 0.25 | 1 / 578 | 15% | 0.54 | 169 / 1155 |
peripheral blood | 14% | 91.35 | 134 / 929 | 0% | 0 | 0 / 0 |
breast | 3% | 4.16 | 12 / 459 | 9% | 0.24 | 99 / 1118 |
esophagus | 0% | 0.88 | 7 / 1445 | 10% | 0.32 | 19 / 183 |
heart | 11% | 23.83 | 93 / 861 | 0% | 0 | 0 / 0 |
thymus | 0% | 0.36 | 1 / 653 | 10% | 0.42 | 58 / 605 |
bladder | 0% | 0 | 0 / 21 | 9% | 0.38 | 46 / 504 |
tonsil | 0% | 0 | 0 / 0 | 7% | 0.33 | 3 / 45 |
liver | 0% | 0 | 0 / 226 | 6% | 0.13 | 26 / 406 |
stomach | 0% | 0 | 0 / 359 | 6% | 0.20 | 18 / 286 |
intestine | 1% | 1.08 | 7 / 966 | 3% | 0.28 | 17 / 527 |
pancreas | 0% | 0 | 0 / 328 | 2% | 0.34 | 4 / 178 |
adipose | 0% | 0.51 | 4 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 0.11 | 1 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006813 | Biological process | potassium ion transport |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0071805 | Biological process | potassium ion transmembrane transport |
GO_0045202 | Cellular component | synapse |
GO_0043025 | Cellular component | neuronal cell body |
GO_0005886 | Cellular component | plasma membrane |
GO_0008076 | Cellular component | voltage-gated potassium channel complex |
GO_0043005 | Cellular component | neuron projection |
GO_0016286 | Molecular function | small conductance calcium-activated potassium channel activity |
GO_0015269 | Molecular function | calcium-activated potassium channel activity |
GO_0005516 | Molecular function | calmodulin binding |
GO_0005242 | Molecular function | inward rectifier potassium channel activity |
Gene name | KCNN1 |
Protein name | Potassium calcium-activated channel subfamily N member 1 Small conductance calcium-activated potassium channel protein 1 (SK1) (SKCa 1) (SKCa1) (KCa2.1) Potassium calcium-activated channel subfamily N member 1 (Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1, isoform CRA_b) |
Synonyms | hCG_36878 SK |
Description | FUNCTION: Forms a voltage-independent potassium channel activated by intracellular calcium . Activation is followed by membrane hyperpolarization (By similarity). Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization (By similarity). . |
Accessions | ENST00000684775.1 [Q92952-1] ENST00000684725.1 ENST00000682733.1 A0A087X2E7 A0A804HIJ6 ENST00000683588.1 ENST00000682726.1 A0A804HIW7 A0A804HK94 ENST00000609922.2 V9GYV2 A0A804HIF9 ENST00000683930.1 Q92952 ENST00000682421.1 ENST00000615435.2 ENST00000222249.13 [Q92952-1] |