Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte precursor cell | 9 studies | 74% ± 23% | |
| GABAergic neuron | 6 studies | 58% ± 19% | |
| glutamatergic neuron | 5 studies | 50% ± 9% | |
| interneuron | 4 studies | 54% ± 13% | |
| pancreatic A cell | 3 studies | 38% ± 11% | |
| type B pancreatic cell | 3 studies | 27% ± 7% | |
| astrocyte | 3 studies | 43% ± 27% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 205.27 | 2621 / 2642 | 56% | 1.40 | 393 / 705 |
| ovary | 99% | 522.99 | 179 / 180 | 50% | 1.60 | 214 / 430 |
| pancreas | 92% | 95.66 | 302 / 328 | 37% | 2.35 | 66 / 178 |
| kidney | 98% | 151.11 | 87 / 89 | 15% | 0.65 | 131 / 901 |
| uterus | 89% | 159.61 | 152 / 170 | 7% | 0.16 | 32 / 459 |
| heart | 94% | 147.88 | 808 / 861 | 0% | 0 | 0 / 0 |
| stomach | 86% | 71.99 | 308 / 359 | 2% | 0.12 | 7 / 286 |
| adrenal gland | 31% | 47.70 | 81 / 258 | 56% | 4.39 | 128 / 230 |
| lung | 66% | 53.07 | 382 / 578 | 11% | 0.23 | 126 / 1155 |
| prostate | 47% | 30.34 | 116 / 245 | 27% | 1.36 | 134 / 502 |
| intestine | 60% | 69.07 | 583 / 966 | 2% | 0.12 | 13 / 527 |
| thymus | 43% | 25.58 | 283 / 653 | 2% | 0.05 | 15 / 605 |
| spleen | 35% | 22.02 | 85 / 241 | 0% | 0 | 0 / 0 |
| esophagus | 29% | 19.06 | 415 / 1445 | 5% | 0.13 | 10 / 183 |
| breast | 22% | 12.48 | 100 / 459 | 1% | 0.05 | 9 / 1118 |
| bladder | 14% | 6.24 | 3 / 21 | 3% | 0.17 | 14 / 504 |
| adipose | 17% | 10.53 | 203 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 13% | 19.01 | 123 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 6% | 2.11 | 74 / 1335 | 0% | 0 | 0 / 0 |
| skin | 2% | 0.75 | 39 / 1809 | 1% | 0.23 | 3 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.04 | 1 / 45 |
| liver | 0% | 0.16 | 1 / 226 | 2% | 0.06 | 7 / 406 |
| muscle | 2% | 0.45 | 13 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006813 | Biological process | potassium ion transport |
| GO_0001508 | Biological process | action potential |
| GO_0019228 | Biological process | neuronal action potential |
| GO_0019229 | Biological process | regulation of vasoconstriction |
| GO_0005513 | Biological process | detection of calcium ion |
| GO_0071805 | Biological process | potassium ion transmembrane transport |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0008076 | Cellular component | voltage-gated potassium channel complex |
| GO_0015269 | Molecular function | calcium-activated potassium channel activity |
| GO_0015459 | Molecular function | potassium channel regulator activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008200 | Molecular function | ion channel inhibitor activity |
| Gene name | KCNMB2 |
| Protein name | Large-conductance Ca2+-activated K+ channel beta2 subunit Calcium-activated potassium channel subunit beta (BKbeta) (BK channel subunit beta) (Calcium-activated potassium channel, subfamily M subunit beta) (Charybdotoxin receptor subunit beta) (K(VCA)beta) (Maxi K channel subunit beta) (Slo-beta) Potassium calcium-activated channel subfamily M regulatory beta subunit 2 Calcium-activated potassium channel subunit beta-2 (BK channel subunit beta-2) (BKbeta2) (Hbeta2) (Calcium-activated potassium channel, subfamily M subunit beta-2) (Charybdotoxin receptor subunit beta-2) (Hbeta3) (K(VCA)beta-2) (Maxi K channel subunit beta-2) (Slo-beta-2) |
| Synonyms | |
| Description | FUNCTION: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons. . FUNCTION: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. . FUNCTION: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. . FUNCTION: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. . FUNCTION: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. . FUNCTION: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. . |
| Accessions | B5BNW5 ENST00000420517.6 ENST00000452583.6 E7EM81 B5BNW6 ENST00000432997.5 B5BNW8 ENST00000455865.5 ENST00000437510.5 B5BNX1 E7ETM2 B5BNW7 ENST00000422927.1 B5BNX0 ENST00000358316.7 B5BNW9 F8WE19 Q9Y691 |
