I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| retinal rod cell | 7 studies | 35% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| retinal rod cell | 7 studies | 35% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| eye | 3 studies | 27% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 94% | 101.94 | 1365 / 1445 | 92% | 2.90 | 169 / 183 |
| brain | 99% | 195.39 | 2603 / 2642 | 80% | 1.69 | 567 / 705 |
| ovary | 99% | 141.76 | 179 / 180 | 73% | 1.75 | 313 / 430 |
| uterus | 100% | 113.08 | 170 / 170 | 69% | 1.54 | 318 / 459 |
| intestine | 98% | 82.98 | 949 / 966 | 67% | 1.36 | 354 / 527 |
| bladder | 100% | 88.62 | 21 / 21 | 58% | 1.20 | 292 / 504 |
| prostate | 99% | 202.86 | 243 / 245 | 54% | 0.83 | 269 / 502 |
| stomach | 91% | 64.47 | 327 / 359 | 61% | 1.30 | 175 / 286 |
| lung | 97% | 107.81 | 563 / 578 | 54% | 1.15 | 623 / 1155 |
| skin | 100% | 255.74 | 1807 / 1809 | 51% | 1.03 | 241 / 472 |
| breast | 98% | 123.31 | 449 / 459 | 46% | 0.79 | 509 / 1118 |
| thymus | 100% | 193.61 | 653 / 653 | 42% | 0.61 | 252 / 605 |
| pancreas | 84% | 50.36 | 277 / 328 | 54% | 0.95 | 97 / 178 |
| kidney | 98% | 87.73 | 87 / 89 | 29% | 0.47 | 261 / 901 |
| liver | 88% | 66.02 | 198 / 226 | 14% | 0.22 | 58 / 406 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.42 | 1 / 1 |
| adrenal gland | 80% | 47.10 | 206 / 258 | 20% | 0.33 | 46 / 230 |
| spleen | 100% | 96.66 | 240 / 241 | 0% | 0 | 0 / 0 |
| muscle | 99% | 140.62 | 795 / 803 | 0% | 0 | 0 / 0 |
| adipose | 98% | 108.44 | 1181 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 86% | 57.93 | 1150 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 76% | 1.57 | 34 / 45 |
| heart | 65% | 37.05 | 560 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 45% | 0.65 | 13 / 29 |
| peripheral blood | 35% | 31.72 | 328 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 31% | 0.75 | 25 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0034765 | Biological process | regulation of monoatomic ion transmembrane transport |
| GO_1990573 | Biological process | potassium ion import across plasma membrane |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0008076 | Cellular component | voltage-gated potassium channel complex |
| GO_0030425 | Cellular component | dendrite |
| GO_0005242 | Molecular function | inward rectifier potassium channel activity |
| Gene name | KCNJ14 |
| Protein name | ATP-sensitive inward rectifier potassium channel 14 (Inward rectifier K(+) channel Kir2.4) (IRK-4) (Potassium channel, inwardly rectifying subfamily J member 14) |
| Synonyms | IRK4 |
| Description | FUNCTION: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium (By similarity). . |
| Accessions | ENST00000391884.2 ENST00000342291.3 Q9UNX9 |
