KCNJ12 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of KCNJ12 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	86%	308.62	560 / 653	84%	3.43	509 / 605
lung	94%	482.38	545 / 578	35%	1.23	410 / 1155
brain	86%	2180.57	2275 / 2642	42%	1.32	293 / 705
kidney	81%	269.35	72 / 89	42%	1.26	375 / 901
stomach	78%	196.64	281 / 359	35%	1.71	100 / 286
skin	72%	499.53	1301 / 1809	41%	2.69	193 / 472
uterus	62%	165.32	105 / 170	49%	3.34	227 / 459
eye	0%	0	0 / 0	100%	13.69	80 / 80
muscle	100%	4945.18	803 / 803	0%	0	0 / 0
intestine	69%	179.96	664 / 966	30%	1.17	158 / 527
heart	98%	1027.66	846 / 861	0%	0	0 / 0
ovary	23%	65.86	42 / 180	75%	4.39	322 / 430
breast	67%	191.67	306 / 459	28%	1.01	317 / 1118
spleen	90%	269.01	218 / 241	0%	0	0 / 0
adrenal gland	25%	75.13	64 / 258	64%	7.57	148 / 230
prostate	31%	76.62	77 / 245	57%	1.57	285 / 502
adipose	76%	255.06	915 / 1204	0%	0	0 / 0
esophagus	37%	93.82	529 / 1445	32%	1.02	59 / 183
bladder	43%	157.19	9 / 21	20%	0.61	100 / 504
pancreas	0%	0.52	1 / 328	42%	0.95	74 / 178
tonsil	0%	0	0 / 0	40%	1.62	18 / 45
blood vessel	31%	79.00	411 / 1335	0%	0	0 / 0
peripheral blood	6%	29.02	60 / 929	0%	0	0 / 0
liver	1%	2.22	2 / 226	3%	0.11	13 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0034765	Biological process	regulation of monoatomic ion transmembrane transport
GO_0006813	Biological process	potassium ion transport
GO_0006936	Biological process	muscle contraction
GO_0008016	Biological process	regulation of heart contraction
GO_1990573	Biological process	potassium ion import across plasma membrane
GO_0051289	Biological process	protein homotetramerization
GO_0034702	Cellular component	monoatomic ion channel complex
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0005515	Molecular function	protein binding
GO_0005242	Molecular function	inward rectifier potassium channel activity

Gene name	KCNJ12
Protein name	ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12) Inwardly rectifying potassium channel Kir2.5 (Potassium inwardly-rectifying channel, subfamily J, member 12)
Synonyms	IRK2 KCNJN1 hCG_1731841 KCNJ17
Description	FUNCTION: Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. .
Accessions	ENST00000583088.6 ENST00000331718.5 Q14500 A0A142K0N8

KCNJ12 report