KCNJ10 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1905515Biological processnon-motile cilium assembly
GO_0007601Biological processvisual perception
GO_0007628Biological processadult walking behavior
GO_0006813Biological processpotassium ion transport
GO_0035865Biological processcellular response to potassium ion
GO_0048169Biological processregulation of long-term neuronal synaptic plasticity
GO_0051935Biological processglutamate reuptake
GO_0055075Biological processpotassium ion homeostasis
GO_0022010Biological processcentral nervous system myelination
GO_0034765Biological processregulation of monoatomic ion transmembrane transport
GO_0060075Biological processregulation of resting membrane potential
GO_1990573Biological processpotassium ion import across plasma membrane
GO_0098793Cellular componentpresynapse
GO_0005886Cellular componentplasma membrane
GO_0034702Cellular componentmonoatomic ion channel complex
GO_0097449Cellular componentastrocyte projection
GO_0097546Cellular componentciliary base
GO_0044297Cellular componentcell body
GO_0016323Cellular componentbasolateral plasma membrane
GO_0005242Molecular functioninward rectifier potassium channel activity
GO_0005524Molecular functionATP binding
GO_0005515Molecular functionprotein binding
GO_0015272Molecular functionATP-activated inward rectifier potassium channel activity

IV. Literature review

[source]
Gene nameKCNJ10
Protein namePotassium inwardly rectifying channel subfamily J member 10
Inwardly-rectifying potassium channel Kir1.2
Potassium inwardly-rectifying channel
ATP-sensitive inward rectifier potassium channel 10 (ATP-dependent inwardly rectifying potassium channel Kir4.1) (Inward rectifier K(+) channel Kir1.2) (Potassium channel, inwardly rectifying subfamily J member 10)
Synonyms
DescriptionFUNCTION: May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity). In the kidney, together with KCNJ16, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules. .

AccessionsENST00000638728.1
A0A1W2PP51
ENST00000638840.1
A0A1W2PPI0
Q9BXC5
ENST00000638868.1
P78508
A0A1W2PQC0
Q547K1
ENST00000644903.1
ENST00000639408.1
A0A1B0GUX2
A0A1W2PP61
ENST00000637644.1
ENST00000509700.2
ENST00000640914.1
ENST00000640017.1
A0A1W2PQP0