Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| pericyte | 20 studies | 29% ± 13% | |
| smooth muscle cell | 9 studies | 30% ± 8% | |
| fibroblast | 5 studies | 33% ± 12% | |
| endothelial cell | 4 studies | 28% ± 8% | |
| myofibroblast cell | 3 studies | 44% ± 16% | |
| astrocyte | 3 studies | 26% ± 10% |
Insufficient scRNA-seq data for expression of KCNE4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 98% | 1167.97 | 450 / 459 | 87% | 74.32 | 971 / 1118 |
| thymus | 100% | 1650.55 | 651 / 653 | 68% | 7.60 | 409 / 605 |
| pancreas | 67% | 864.28 | 219 / 328 | 90% | 23.15 | 161 / 178 |
| stomach | 94% | 1697.96 | 337 / 359 | 47% | 5.37 | 133 / 286 |
| kidney | 73% | 595.87 | 65 / 89 | 65% | 19.75 | 587 / 901 |
| bladder | 100% | 1777.48 | 21 / 21 | 38% | 4.34 | 191 / 504 |
| adrenal gland | 66% | 420.74 | 171 / 258 | 63% | 11.91 | 145 / 230 |
| skin | 71% | 652.90 | 1287 / 1809 | 56% | 8.34 | 266 / 472 |
| uterus | 95% | 2913.22 | 162 / 170 | 29% | 11.77 | 135 / 459 |
| ovary | 94% | 1847.81 | 170 / 180 | 29% | 2.98 | 125 / 430 |
| brain | 55% | 390.04 | 1463 / 2642 | 62% | 12.60 | 434 / 705 |
| intestine | 79% | 896.49 | 762 / 966 | 37% | 4.59 | 195 / 527 |
| lung | 51% | 426.08 | 292 / 578 | 60% | 11.60 | 692 / 1155 |
| esophagus | 70% | 1014.90 | 1016 / 1445 | 33% | 3.03 | 60 / 183 |
| prostate | 78% | 729.67 | 191 / 245 | 25% | 1.58 | 124 / 502 |
| blood vessel | 100% | 3227.59 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 2064.04 | 1199 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 90% | 19.38 | 72 / 80 |
| heart | 84% | 1045.31 | 726 / 861 | 0% | 0 | 0 / 0 |
| muscle | 79% | 458.98 | 634 / 803 | 0% | 0 | 0 / 0 |
| spleen | 75% | 620.32 | 181 / 241 | 0% | 0 | 0 / 0 |
| liver | 29% | 181.35 | 65 / 226 | 25% | 2.99 | 100 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 48% | 4.49 | 14 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 2.15 | 11 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1902260 | Biological process | negative regulation of delayed rectifier potassium channel activity |
| GO_0060307 | Biological process | regulation of ventricular cardiac muscle cell membrane repolarization |
| GO_0086011 | Biological process | membrane repolarization during action potential |
| GO_0097623 | Biological process | potassium ion export across plasma membrane |
| GO_0086005 | Biological process | ventricular cardiac muscle cell action potential |
| GO_0098915 | Biological process | membrane repolarization during ventricular cardiac muscle cell action potential |
| GO_0086091 | Biological process | regulation of heart rate by cardiac conduction |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0008076 | Cellular component | voltage-gated potassium channel complex |
| GO_0005251 | Molecular function | delayed rectifier potassium channel activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0015459 | Molecular function | potassium channel regulator activity |
| GO_1902282 | Molecular function | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization |
| GO_0044325 | Molecular function | transmembrane transporter binding |
| Gene name | KCNE4 |
| Protein name | Potassium voltage-gated channel subfamily E member 4 (MinK-related peptide 3) (Minimum potassium ion channel-related peptide 3) (Potassium channel subunit beta MiRP3) Cardiac voltage-gated potassium channel accessory subunit 4 |
| Synonyms | |
| Description | FUNCTION: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associates with KCNQ1/KVLTQ1 and inhibits potassium currents. .; FUNCTION: [Isoform 2]: May inhibit KCNQ4-mediated potassium currents. . |
| Accessions | Q8WWG9 ENST00000281830.4 [Q8WWG9-3] Q2N1I0 |
