Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 12 studies | 39% ± 15% | |
| macrophage | 8 studies | 21% ± 6% | |
| monocyte | 5 studies | 27% ± 7% | |
| myeloid cell | 4 studies | 23% ± 9% | |
| adipocyte | 3 studies | 26% ± 7% | |
| mononuclear phagocyte | 3 studies | 21% ± 3% | |
| alveolar macrophage | 3 studies | 41% ± 10% |
Insufficient scRNA-seq data for expression of KCNE1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 564.54 | 578 / 578 | 10% | 0.20 | 115 / 1155 |
| spleen | 100% | 594.18 | 241 / 241 | 0% | 0 | 0 / 0 |
| liver | 96% | 300.03 | 217 / 226 | 0% | 0.01 | 2 / 406 |
| adipose | 87% | 167.38 | 1052 / 1204 | 0% | 0 | 0 / 0 |
| heart | 87% | 94.16 | 752 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 85% | 74.72 | 219 / 258 | 1% | 0.01 | 2 / 230 |
| kidney | 83% | 70.43 | 74 / 89 | 2% | 0.05 | 20 / 901 |
| peripheral blood | 81% | 1198.83 | 755 / 929 | 0% | 0 | 0 / 0 |
| breast | 78% | 100.30 | 360 / 459 | 2% | 0.03 | 23 / 1118 |
| bladder | 71% | 84.67 | 15 / 21 | 1% | 0.02 | 6 / 504 |
| intestine | 68% | 52.60 | 661 / 966 | 2% | 0.02 | 8 / 527 |
| esophagus | 55% | 38.74 | 789 / 1445 | 1% | 0.01 | 2 / 183 |
| blood vessel | 47% | 50.78 | 634 / 1335 | 0% | 0 | 0 / 0 |
| stomach | 44% | 31.26 | 157 / 359 | 3% | 0.04 | 8 / 286 |
| prostate | 45% | 39.84 | 110 / 245 | 1% | 0.01 | 3 / 502 |
| thymus | 41% | 21.15 | 266 / 653 | 0% | 0.00 | 2 / 605 |
| ovary | 35% | 20.11 | 63 / 180 | 4% | 0.08 | 18 / 430 |
| uterus | 35% | 20.49 | 59 / 170 | 4% | 0.08 | 19 / 459 |
| pancreas | 19% | 10.27 | 63 / 328 | 3% | 0.07 | 6 / 178 |
| skin | 17% | 7.66 | 312 / 1809 | 5% | 0.14 | 22 / 472 |
| lymph node | 0% | 0 | 0 / 0 | 17% | 0.36 | 5 / 29 |
| brain | 8% | 4.69 | 213 / 2642 | 1% | 0.03 | 10 / 705 |
| muscle | 8% | 3.22 | 67 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1901381 | Biological process | positive regulation of potassium ion transmembrane transport |
| GO_0007605 | Biological process | sensory perception of sound |
| GO_0060307 | Biological process | regulation of ventricular cardiac muscle cell membrane repolarization |
| GO_1902259 | Biological process | regulation of delayed rectifier potassium channel activity |
| GO_0033363 | Biological process | secretory granule organization |
| GO_0021750 | Biological process | vestibular nucleus development |
| GO_0086002 | Biological process | cardiac muscle cell action potential involved in contraction |
| GO_1901379 | Biological process | regulation of potassium ion transmembrane transport |
| GO_0071482 | Biological process | cellular response to light stimulus |
| GO_0086011 | Biological process | membrane repolarization during action potential |
| GO_0086005 | Biological process | ventricular cardiac muscle cell action potential |
| GO_0098915 | Biological process | membrane repolarization during ventricular cardiac muscle cell action potential |
| GO_0086003 | Biological process | cardiac muscle cell contraction |
| GO_0086013 | Biological process | membrane repolarization during cardiac muscle cell action potential |
| GO_0071468 | Biological process | cellular response to acidic pH |
| GO_0071805 | Biological process | potassium ion transmembrane transport |
| GO_0002070 | Biological process | epithelial cell maturation |
| GO_1902260 | Biological process | negative regulation of delayed rectifier potassium channel activity |
| GO_0071320 | Biological process | cellular response to cAMP |
| GO_0097623 | Biological process | potassium ion export across plasma membrane |
| GO_0086091 | Biological process | regulation of heart rate by cardiac conduction |
| GO_0090315 | Biological process | negative regulation of protein targeting to membrane |
| GO_0008584 | Biological process | male gonad development |
| GO_0086009 | Biological process | membrane repolarization |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0045121 | Cellular component | membrane raft |
| GO_0030018 | Cellular component | Z disc |
| GO_0005764 | Cellular component | lysosome |
| GO_0009986 | Cellular component | cell surface |
| GO_0008076 | Cellular component | voltage-gated potassium channel complex |
| GO_0005249 | Molecular function | voltage-gated potassium channel activity |
| GO_0005251 | Molecular function | delayed rectifier potassium channel activity |
| GO_1902282 | Molecular function | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization |
| GO_0044877 | Molecular function | protein-containing complex binding |
| GO_0031433 | Molecular function | telethonin binding |
| GO_0086008 | Molecular function | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization |
| GO_0015459 | Molecular function | potassium channel regulator activity |
| GO_0044325 | Molecular function | transmembrane transporter binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | KCNE1 |
| Protein name | Potassium voltage-gated channel subfamily E member 1 (Delayed rectifier potassium channel subunit IsK) (IKs producing slow voltage-gated potassium channel subunit beta Mink) (Minimal potassium channel) Potassium voltage-gated channel subfamily E member 1 |
| Synonyms | |
| Description | FUNCTION: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 . Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr). . |
| Accessions | ENST00000399286.3 ENST00000621601.4 A7LFK4 ENST00000432085.5 ENST00000337385.7 ENST00000399289.7 ENST00000611936.1 ENST00000399284.1 Q6FHJ6 A7LFK2 P15382 Q5DI96 C7S316 ENST00000416357.6 |
