JMJD4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of JMJD4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of JMJD4 at tissue level.

III. Associated gene sets

GO_0045905Biological processpositive regulation of translational termination
GO_0018126Biological processprotein hydroxylation
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0106156Molecular functionpeptidyl-lysine 4-dioxygenase activity
GO_0005515Molecular functionprotein binding
GO_0043565Molecular functionsequence-specific DNA binding
GO_0046872Molecular functionmetal ion binding
GO_0016706Molecular function2-oxoglutarate-dependent dioxygenase activity

IV. Literature review

[source]
Gene nameJMJD4
Protein nameAlternative protein JMJD4
2-oxoglutarate and iron-dependent oxygenase JMJD4 (EC 1.14.11.-) (JmjC domain-containing protein 4) (Jumonji domain-containing protein 4) (Lysyl-hydroxylase JMJD4)
Synonyms
DescriptionFUNCTION: Catalyzes the 2-oxoglutarate and iron-dependent C4-lysyl hydroxylation of ETF1 at 'Lys-63' thereby promoting the translational termination efficiency of ETF1. .

AccessionsQ9H9V9
ENST00000620518.5 [Q9H9V9-3]
ENST00000438896.3 [Q9H9V9-2]
L8ECK0