Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 36% ± 13% | |
| oligodendrocyte | 4 studies | 25% ± 7% | |
| natural killer cell | 3 studies | 17% ± 2% | |
| GABAergic neuron | 3 studies | 35% ± 10% | |
| interneuron | 3 studies | 31% ± 18% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 29% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 4122.43 | 653 / 653 | 100% | 29.69 | 604 / 605 |
| intestine | 100% | 3891.08 | 966 / 966 | 99% | 17.26 | 524 / 527 |
| adrenal gland | 100% | 5247.64 | 258 / 258 | 99% | 31.85 | 228 / 230 |
| kidney | 100% | 2997.26 | 89 / 89 | 99% | 25.17 | 890 / 901 |
| lung | 100% | 3476.91 | 577 / 578 | 99% | 23.10 | 1141 / 1155 |
| stomach | 99% | 2855.19 | 356 / 359 | 99% | 19.61 | 284 / 286 |
| skin | 100% | 2952.03 | 1807 / 1809 | 99% | 29.80 | 465 / 472 |
| brain | 99% | 3382.53 | 2621 / 2642 | 99% | 16.88 | 695 / 705 |
| prostate | 100% | 3834.51 | 245 / 245 | 97% | 13.61 | 488 / 502 |
| esophagus | 99% | 3489.13 | 1431 / 1445 | 98% | 30.39 | 179 / 183 |
| breast | 99% | 3651.66 | 456 / 459 | 96% | 22.83 | 1076 / 1118 |
| ovary | 100% | 4226.03 | 180 / 180 | 95% | 17.03 | 410 / 430 |
| pancreas | 96% | 2086.09 | 316 / 328 | 99% | 21.47 | 176 / 178 |
| uterus | 100% | 4180.17 | 170 / 170 | 92% | 16.20 | 422 / 459 |
| bladder | 100% | 4651.52 | 21 / 21 | 91% | 14.28 | 461 / 504 |
| liver | 59% | 492.36 | 133 / 226 | 65% | 6.52 | 264 / 406 |
| eye | 0% | 0 | 0 / 0 | 100% | 24.84 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 46.66 | 29 / 29 |
| spleen | 100% | 5664.40 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 36.50 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.23 | 1 / 1 |
| blood vessel | 100% | 3883.09 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 3489.02 | 1201 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 97% | 1647.02 | 777 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 1905.87 | 833 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 95% | 3232.63 | 884 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0016567 | Biological process | protein ubiquitination |
| GO_0006275 | Biological process | regulation of DNA replication |
| GO_0001558 | Biological process | regulation of cell growth |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0006338 | Biological process | chromatin remodeling |
| GO_0051726 | Biological process | regulation of cell cycle |
| GO_2000278 | Biological process | regulation of DNA biosynthetic process |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000123 | Cellular component | histone acetyltransferase complex |
| GO_0043996 | Molecular function | histone H4K8 acetyltransferase activity |
| GO_0046972 | Molecular function | histone H4K16 acetyltransferase activity |
| GO_0043997 | Molecular function | histone H4K12 acetyltransferase activity |
| GO_0043995 | Molecular function | histone H4K5 acetyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0036408 | Molecular function | histone H3K14 acetyltransferase activity |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | JADE2 |
| Protein name | Jade family PHD finger 2 Jade family PHD finger 2 (PHD finger protein 15, isoform CRA_d) E3 ubiquitin-protein ligase Jade-2 (EC 2.3.2.27) (Jade family PHD finger protein 2) (PHD finger protein 15) E3 ubiquitin-protein ligase Jade-2 |
| Synonyms | PHF15 KIAA0239 hCG_16590 |
| Description | FUNCTION: Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity . Acts as an E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A . Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis (By similarity). . |
| Accessions | A0A7P0TAP8 A0A7P0T8T0 ENST00000681820.1 ENST00000402835.5 H7C0P2 A0A087X085 ENST00000681547.2 Q9NQC1 ENST00000431355.2 A0A7P0Z4H4 G3XAA4 C9J929 ENST00000612830.2 ENST00000681019.1 B5MBX1 ENST00000681498.1 ENST00000430087 ENST00000430087.2 [Q9NQC1-3] ENST00000395003.5 [Q9NQC1-1] ENST00000361895.6 ENST00000512386.6 ENST00000282605.8 ENST00000680418.1 A0A0C4DFT8 |
