IVD report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006552Biological processL-leucine catabolic process
GO_0009083Biological processbranched-chain amino acid catabolic process
GO_0033539Biological processfatty acid beta-oxidation using acyl-CoA dehydrogenase
GO_0005654Cellular componentnucleoplasm
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0008470Molecular functionisovaleryl-CoA dehydrogenase activity
GO_0004085Molecular functionbutyryl-CoA dehydrogenase activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0050660Molecular functionflavin adenine dinucleotide binding

IV. Literature review

[source]
Gene nameIVD
Protein nameTruncated isovalery CoA dehydrogenase
Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4) (Butyryl-CoA dehydrogenase) (EC 1.3.8.1)
Isovaleryl-CoA dehydrogenase, mitochondrial (EC 1.3.8.1) (EC 1.3.8.4) (Butyryl-CoA dehydrogenase)
Isovaleryl-CoA dehydrogenase
Isovaleryl-CoA dehydrogenase isoform 3
Synonyms
DescriptionFUNCTION: Catalyzes the conversion of isovaleryl-CoA/3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA as an intermediate step in the leucine (Leu) catabolic pathway . To a lesser extent, is also able to catalyze the oxidation of other saturated short-chain acyl-CoA thioesters as pentanoyl-CoA, hexenoyl-CoA and butenoyl-CoA . .

AccessionsENST00000650656.1 [P26440-2]
ENST00000491554.6
H0YNA4
H7C4G6
A0A2L0RI76
ENST00000610693.5
ENST00000487418.8
A0A087WVD3
A0A0S2Z3Z7
A0A2L0RIB1
P26440
ENST00000481262.6
H0YKV0
ENST00000466756.2
H0YN10
H0YLC3
ENST00000651168.1 [P26440-1]
ENST00000558610.5
A0A2L0RI93
A0A2L0RIE3
ENST00000559575.5
A0A0S2Z4K7
ENST00000473112.6
A0A0A0MT83
ENST00000479013.7
O43577
H0YNT5
A0A2L0RI88