Name | Number of supported studies | Average coverage | |
---|---|---|---|
plasmacytoid dendritic cell | 10 studies | 23% ± 7% | |
epithelial cell | 6 studies | 26% ± 7% | |
endothelial cell | 5 studies | 20% ± 2% | |
oligodendrocyte precursor cell | 5 studies | 30% ± 9% | |
astrocyte | 4 studies | 28% ± 9% | |
microglial cell | 4 studies | 26% ± 8% | |
macrophage | 4 studies | 18% ± 3% | |
fibroblast | 3 studies | 16% ± 0% | |
GABAergic neuron | 3 studies | 34% ± 11% | |
glutamatergic neuron | 3 studies | 41% ± 15% | |
abnormal cell | 3 studies | 24% ± 4% | |
oligodendrocyte | 3 studies | 25% ± 6% | |
hepatocyte | 3 studies | 22% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 13389.58 | 226 / 226 | 100% | 60.57 | 406 / 406 |
brain | 100% | 5392.08 | 2640 / 2642 | 100% | 62.44 | 705 / 705 |
prostate | 100% | 7490.44 | 245 / 245 | 100% | 110.02 | 500 / 502 |
adrenal gland | 100% | 13141.65 | 258 / 258 | 100% | 60.53 | 229 / 230 |
thymus | 100% | 23593.94 | 653 / 653 | 100% | 88.40 | 602 / 605 |
kidney | 100% | 6983.80 | 89 / 89 | 99% | 46.19 | 896 / 901 |
pancreas | 99% | 2497.60 | 326 / 328 | 99% | 35.93 | 177 / 178 |
ovary | 100% | 5677.43 | 180 / 180 | 99% | 30.28 | 424 / 430 |
intestine | 100% | 4708.53 | 966 / 966 | 98% | 35.81 | 515 / 527 |
bladder | 100% | 4660.00 | 21 / 21 | 97% | 31.65 | 488 / 504 |
breast | 100% | 4029.63 | 459 / 459 | 96% | 52.90 | 1078 / 1118 |
lung | 99% | 4170.02 | 573 / 578 | 97% | 32.57 | 1122 / 1155 |
stomach | 100% | 5794.86 | 359 / 359 | 96% | 31.54 | 274 / 286 |
esophagus | 99% | 3386.64 | 1432 / 1445 | 93% | 27.24 | 170 / 183 |
uterus | 100% | 4363.02 | 170 / 170 | 91% | 26.64 | 418 / 459 |
skin | 75% | 2302.68 | 1362 / 1809 | 91% | 32.18 | 429 / 472 |
adipose | 100% | 3482.56 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 26.50 | 29 / 29 |
spleen | 100% | 4661.17 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 21.12 | 1 / 1 |
blood vessel | 99% | 3374.83 | 1328 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 3623.75 | 794 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 39.07 | 79 / 80 |
heart | 97% | 5030.41 | 839 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 20.59 | 42 / 45 |
peripheral blood | 57% | 1641.81 | 525 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006552 | Biological process | L-leucine catabolic process |
GO_0009083 | Biological process | branched-chain amino acid catabolic process |
GO_0033539 | Biological process | fatty acid beta-oxidation using acyl-CoA dehydrogenase |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0005739 | Cellular component | mitochondrion |
GO_0008470 | Molecular function | isovaleryl-CoA dehydrogenase activity |
GO_0004085 | Molecular function | butyryl-CoA dehydrogenase activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0050660 | Molecular function | flavin adenine dinucleotide binding |
Gene name | IVD |
Protein name | Truncated isovalery CoA dehydrogenase Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4) (Butyryl-CoA dehydrogenase) (EC 1.3.8.1) Isovaleryl-CoA dehydrogenase, mitochondrial (EC 1.3.8.1) (EC 1.3.8.4) (Butyryl-CoA dehydrogenase) Isovaleryl-CoA dehydrogenase Isovaleryl-CoA dehydrogenase isoform 3 |
Synonyms | |
Description | FUNCTION: Catalyzes the conversion of isovaleryl-CoA/3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA as an intermediate step in the leucine (Leu) catabolic pathway . To a lesser extent, is also able to catalyze the oxidation of other saturated short-chain acyl-CoA thioesters as pentanoyl-CoA, hexenoyl-CoA and butenoyl-CoA . . |
Accessions | ENST00000650656.1 [P26440-2] ENST00000491554.6 H0YNA4 H7C4G6 A0A2L0RI76 ENST00000610693.5 ENST00000487418.8 A0A087WVD3 A0A0S2Z3Z7 A0A2L0RIB1 P26440 ENST00000481262.6 H0YKV0 ENST00000466756.2 H0YN10 H0YLC3 ENST00000651168.1 [P26440-1] ENST00000558610.5 A0A2L0RI93 A0A2L0RIE3 ENST00000559575.5 A0A0S2Z4K7 ENST00000473112.6 A0A0A0MT83 ENST00000479013.7 O43577 H0YNT5 A0A2L0RI88 |