Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 9 studies | 22% ± 8% | |
type II pneumocyte | 7 studies | 19% ± 2% | |
epithelial cell | 5 studies | 36% ± 19% | |
ciliated cell | 5 studies | 24% ± 10% | |
basal cell | 5 studies | 23% ± 4% | |
endothelial cell of vascular tree | 5 studies | 26% ± 7% | |
type I pneumocyte | 4 studies | 22% ± 6% | |
squamous epithelial cell | 4 studies | 50% ± 21% | |
secretory cell | 4 studies | 29% ± 5% | |
vein endothelial cell | 4 studies | 23% ± 5% | |
club cell | 3 studies | 23% ± 10% | |
luminal cell of prostate epithelium | 3 studies | 20% ± 1% |
Insufficient scRNA-seq data for expression of ITPKC at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
uterus | 100% | 3001.78 | 170 / 170 | 100% | 94.19 | 459 / 459 |
esophagus | 100% | 6668.59 | 1444 / 1445 | 100% | 72.09 | 183 / 183 |
lung | 100% | 6507.87 | 578 / 578 | 100% | 64.93 | 1154 / 1155 |
prostate | 100% | 4372.58 | 245 / 245 | 100% | 57.70 | 501 / 502 |
skin | 100% | 5946.70 | 1809 / 1809 | 99% | 31.48 | 469 / 472 |
breast | 100% | 4754.22 | 458 / 459 | 100% | 47.44 | 1113 / 1118 |
intestine | 100% | 2585.46 | 964 / 966 | 99% | 42.12 | 524 / 527 |
thymus | 99% | 2923.71 | 649 / 653 | 100% | 46.26 | 603 / 605 |
bladder | 100% | 3075.00 | 21 / 21 | 99% | 66.08 | 499 / 504 |
stomach | 99% | 3140.64 | 354 / 359 | 99% | 38.60 | 282 / 286 |
kidney | 98% | 2532.78 | 87 / 89 | 99% | 39.44 | 895 / 901 |
ovary | 99% | 1929.96 | 178 / 180 | 97% | 29.81 | 418 / 430 |
adrenal gland | 100% | 2016.02 | 257 / 258 | 93% | 20.34 | 213 / 230 |
pancreas | 87% | 1464.18 | 285 / 328 | 99% | 72.75 | 177 / 178 |
liver | 73% | 1299.71 | 166 / 226 | 98% | 30.29 | 399 / 406 |
brain | 53% | 831.93 | 1412 / 2642 | 95% | 28.23 | 673 / 705 |
eye | 0% | 0 | 0 / 0 | 100% | 23.84 | 80 / 80 |
tonsil | 0% | 0 | 0 / 0 | 100% | 92.87 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 38.11 | 1 / 1 |
adipose | 100% | 5640.90 | 1202 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 2957.12 | 1328 / 1335 | 0% | 0 | 0 / 0 |
spleen | 99% | 2280.31 | 239 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 19.29 | 28 / 29 |
heart | 89% | 1741.91 | 763 / 861 | 0% | 0 | 0 / 0 |
muscle | 78% | 1562.22 | 625 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 67% | 2715.29 | 625 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0032958 | Biological process | inositol phosphate biosynthetic process |
GO_0046854 | Biological process | phosphatidylinositol phosphate biosynthetic process |
GO_0071277 | Biological process | cellular response to calcium ion |
GO_0016607 | Cellular component | nuclear speck |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005516 | Molecular function | calmodulin binding |
GO_0008440 | Molecular function | inositol-1,4,5-trisphosphate 3-kinase activity |
GO_0051765 | Molecular function | inositol tetrakisphosphate kinase activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | ITPKC |
Protein name | Kinase (EC 2.7.-.-) Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase C) (IP3 3-kinase C) (IP3K C) (InsP 3-kinase C) Inositol-trisphosphate 3-kinase C |
Synonyms | IP3KC |
Description | FUNCTION: Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis . Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate (By similarity). . |
Accessions | A0A8V8TNF9 Q96DU7 M0R2L7 ENST00000699489.1 A0A8V8TPP3 ENST00000699488.1 ENST00000597003.1 ENST00000699490.1 ENST00000263370.3 |