Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 7 studies | 23% ± 8% | |
| epithelial cell | 5 studies | 22% ± 5% | |
| astrocyte | 5 studies | 29% ± 8% | |
| microglial cell | 4 studies | 20% ± 3% | |
| GABAergic neuron | 4 studies | 44% ± 15% | |
| glutamatergic neuron | 4 studies | 53% ± 17% | |
| oligodendrocyte precursor cell | 4 studies | 30% ± 9% | |
| interneuron | 4 studies | 38% ± 22% | |
| oligodendrocyte | 4 studies | 24% ± 4% | |
| ciliated cell | 3 studies | 19% ± 3% | |
| retina horizontal cell | 3 studies | 24% ± 6% | |
| macrophage | 3 studies | 22% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 37% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1880.02 | 1445 / 1445 | 100% | 22.99 | 183 / 183 |
| lung | 100% | 1588.61 | 578 / 578 | 100% | 18.90 | 1155 / 1155 |
| breast | 100% | 1846.14 | 459 / 459 | 100% | 24.67 | 1116 / 1118 |
| stomach | 100% | 1666.42 | 359 / 359 | 100% | 21.22 | 285 / 286 |
| intestine | 100% | 2308.74 | 966 / 966 | 100% | 20.34 | 525 / 527 |
| ovary | 100% | 2444.77 | 180 / 180 | 100% | 13.97 | 428 / 430 |
| bladder | 100% | 2101.38 | 21 / 21 | 99% | 18.14 | 500 / 504 |
| uterus | 100% | 2818.34 | 170 / 170 | 99% | 16.21 | 454 / 459 |
| prostate | 100% | 2028.08 | 245 / 245 | 99% | 14.81 | 495 / 502 |
| thymus | 100% | 2267.58 | 653 / 653 | 98% | 10.18 | 595 / 605 |
| pancreas | 100% | 1559.21 | 328 / 328 | 98% | 11.75 | 175 / 178 |
| brain | 98% | 1050.12 | 2590 / 2642 | 99% | 9.90 | 700 / 705 |
| skin | 100% | 1941.94 | 1808 / 1809 | 95% | 15.15 | 450 / 472 |
| kidney | 100% | 1175.10 | 89 / 89 | 94% | 8.89 | 843 / 901 |
| adrenal gland | 100% | 1292.24 | 257 / 258 | 92% | 8.25 | 212 / 230 |
| liver | 99% | 742.19 | 224 / 226 | 87% | 7.59 | 352 / 406 |
| adipose | 100% | 1757.93 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1742.76 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 15.41 | 29 / 29 |
| muscle | 100% | 1344.86 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2284.97 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 14.07 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 10.13 | 1 / 1 |
| heart | 97% | 1234.31 | 839 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 95% | 1819.49 | 879 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 88% | 11.00 | 70 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0034243 | Biological process | regulation of transcription elongation by RNA polymerase II |
| GO_0016180 | Biological process | snRNA processing |
| GO_0034472 | Biological process | snRNA 3'-end processing |
| GO_0032039 | Cellular component | integrator complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | INTS8 |
| Protein name | Integrator complex subunit 8 Integrator complex subunit 8 (Int8) (Protein kaonashi-1) |
| Synonyms | C8orf52 |
| Description | FUNCTION: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. . |
| Accessions | Q75QN2 ENST00000523731.6 [Q75QN2-1] H0YC12 H0YBQ1 H0YBS1 ENST00000523808.5 E5RH10 E5RJL5 J3KNV5 E5RIN8 E5RG48 ENST00000519457.5 ENST00000520315.5 ENST00000524333.5 E5RJF0 ENST00000343161.8 ENST00000523206.5 ENST00000519053.5 ENST00000521860.5 ENST00000522171.5 ENST00000520526.5 |