INTS7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034243Biological processregulation of transcription elongation by RNA polymerase II
GO_0016180Biological processsnRNA processing
GO_0034472Biological processsnRNA 3'-end processing
GO_0071479Biological processcellular response to ionizing radiation
GO_0000077Biological processDNA damage checkpoint signaling
GO_0032039Cellular componentintegrator complex
GO_0005694Cellular componentchromosome
GO_0016604Cellular componentnuclear body
GO_0005654Cellular componentnucleoplasm
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameINTS7
Protein nameIntegrator complex subunit 7
Integrator complex subunit 7 (Int7)
SynonymsC1orf73
DescriptionFUNCTION: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Plays a role in DNA damage response (DDR) signaling during the S phase . May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex . .

AccessionsENST00000366994.8 [Q9NVH2-1]
ENST00000612340.1
A0A087X1Q0
ENST00000440600.6 [Q9NVH2-4]
A0A087WXK3
ENST00000469606.5
ENST00000366993.7 [Q9NVH2-2]
ENST00000366992.7 [Q9NVH2-3]
A0A087WYC2
ENST00000619805.1
Q9NVH2
ENST00000475798.5
A0A087X0F3