INTS5 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of INTS5 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of INTS5 at tissue level.

III. Associated gene sets

GO_0034243Biological processregulation of transcription elongation by RNA polymerase II
GO_0016180Biological processsnRNA processing
GO_0034472Biological processsnRNA 3'-end processing
GO_0032039Cellular componentintegrator complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0031965Cellular componentnuclear membrane
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameINTS5
Protein nameIntegrator complex subunit 5 (Int5)
SynonymsKIAA1698
DescriptionFUNCTION: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex . .

AccessionsENST00000330574.2
Q6P9B9