Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 4 studies | 25% ± 6% | |
| glutamatergic neuron | 4 studies | 34% ± 11% | |
| oligodendrocyte | 4 studies | 22% ± 4% | |
| epithelial cell | 3 studies | 22% ± 1% | |
| GABAergic neuron | 3 studies | 36% ± 1% | |
| oligodendrocyte precursor cell | 3 studies | 19% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 32% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 890.75 | 1445 / 1445 | 100% | 11.72 | 183 / 183 |
| brain | 100% | 926.21 | 2638 / 2642 | 99% | 9.44 | 701 / 705 |
| lung | 100% | 823.06 | 578 / 578 | 99% | 8.23 | 1144 / 1155 |
| stomach | 100% | 659.58 | 359 / 359 | 98% | 8.16 | 281 / 286 |
| intestine | 100% | 847.18 | 966 / 966 | 98% | 7.31 | 515 / 527 |
| breast | 100% | 942.31 | 459 / 459 | 97% | 10.06 | 1080 / 1118 |
| bladder | 100% | 810.00 | 21 / 21 | 96% | 7.23 | 483 / 504 |
| pancreas | 98% | 376.21 | 323 / 328 | 95% | 5.22 | 169 / 178 |
| uterus | 100% | 1035.66 | 170 / 170 | 93% | 6.51 | 425 / 459 |
| kidney | 100% | 524.62 | 89 / 89 | 92% | 6.42 | 832 / 901 |
| prostate | 100% | 761.66 | 245 / 245 | 92% | 5.20 | 460 / 502 |
| thymus | 100% | 876.55 | 653 / 653 | 89% | 4.50 | 541 / 605 |
| skin | 100% | 1211.34 | 1809 / 1809 | 89% | 7.35 | 422 / 472 |
| ovary | 100% | 874.37 | 180 / 180 | 89% | 4.43 | 382 / 430 |
| adrenal gland | 100% | 857.47 | 257 / 258 | 83% | 4.34 | 191 / 230 |
| liver | 100% | 427.26 | 226 / 226 | 60% | 2.61 | 245 / 406 |
| adipose | 100% | 932.33 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 7.31 | 29 / 29 |
| spleen | 100% | 1031.02 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 814.50 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 520.35 | 799 / 803 | 0% | 0 | 0 / 0 |
| heart | 96% | 608.39 | 826 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 6.25 | 41 / 45 |
| eye | 0% | 0 | 0 / 0 | 51% | 2.02 | 41 / 80 |
| peripheral blood | 49% | 718.65 | 459 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0034243 | Biological process | regulation of transcription elongation by RNA polymerase II |
| GO_0016180 | Biological process | snRNA processing |
| GO_0034472 | Biological process | snRNA 3'-end processing |
| GO_0032039 | Cellular component | integrator complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0031965 | Cellular component | nuclear membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | INTS2 |
| Protein name | Integrator complex subunit 2 (Int2) Integrator complex subunit 2 |
| Synonyms | KIAA1287 |
| Description | FUNCTION: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex . . |
| Accessions | ENST00000647009.1 ENST00000251334.7 A0A2R8Y4Z6 A0A2R8Y7F8 J3KMZ7 J3KRH0 ENST00000583076.1 ENST00000444766.7 Q9H0H0 ENST00000646954.1 ENST00000646745.1 |
