Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 6 studies | 22% ± 7% | |
| endothelial cell | 5 studies | 23% ± 7% | |
| neuron | 3 studies | 20% ± 4% | |
| glutamatergic neuron | 3 studies | 43% ± 18% | |
| astrocyte | 3 studies | 18% ± 2% |
Insufficient scRNA-seq data for expression of INTS1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 7634.90 | 1445 / 1445 | 100% | 99.97 | 183 / 183 |
| thymus | 100% | 10492.10 | 653 / 653 | 100% | 54.01 | 603 / 605 |
| skin | 100% | 8201.38 | 1809 / 1809 | 100% | 93.62 | 470 / 472 |
| uterus | 100% | 10239.88 | 170 / 170 | 100% | 58.99 | 457 / 459 |
| liver | 100% | 4817.63 | 226 / 226 | 100% | 36.90 | 404 / 406 |
| pancreas | 100% | 6493.03 | 328 / 328 | 99% | 47.50 | 177 / 178 |
| intestine | 100% | 8538.62 | 966 / 966 | 99% | 66.44 | 524 / 527 |
| prostate | 100% | 9826.35 | 245 / 245 | 99% | 57.39 | 499 / 502 |
| breast | 100% | 7862.97 | 459 / 459 | 99% | 51.09 | 1107 / 1118 |
| stomach | 100% | 6612.87 | 359 / 359 | 99% | 67.95 | 283 / 286 |
| ovary | 100% | 9652.38 | 180 / 180 | 99% | 56.67 | 425 / 430 |
| kidney | 100% | 7734.17 | 89 / 89 | 99% | 43.24 | 890 / 901 |
| bladder | 100% | 8054.86 | 21 / 21 | 99% | 59.17 | 497 / 504 |
| brain | 99% | 7401.24 | 2626 / 2642 | 99% | 62.69 | 699 / 705 |
| adrenal gland | 100% | 7310.88 | 258 / 258 | 98% | 40.76 | 226 / 230 |
| lung | 100% | 7660.29 | 577 / 578 | 98% | 60.64 | 1134 / 1155 |
| adipose | 100% | 6931.13 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 73.44 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 64.13 | 29 / 29 |
| muscle | 100% | 11042.64 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 9771.00 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 59.80 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 27.39 | 1 / 1 |
| blood vessel | 100% | 8109.42 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 5111.43 | 850 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 6066.44 | 910 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0001833 | Biological process | inner cell mass cell proliferation |
| GO_0034474 | Biological process | U2 snRNA 3'-end processing |
| GO_0034243 | Biological process | regulation of transcription elongation by RNA polymerase II |
| GO_0016180 | Biological process | snRNA processing |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0007566 | Biological process | embryo implantation |
| GO_0032039 | Cellular component | integrator complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0031965 | Cellular component | nuclear membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005634 | Cellular component | nucleus |
| Gene name | INTS1 |
| Protein name | Integrator complex subunit 1 (Int1) Integrator complex subunit 1 |
| Synonyms | KIAA1440 UNQ1821/PRO3434 |
| Description | FUNCTION: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex . . |
| Accessions | H7C582 Q8N201 ENST00000404767.8 ENST00000483196.1 |
