INPP5A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1900737Biological processnegative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway
GO_0046856Biological processphosphatidylinositol dephosphorylation
GO_0043647Biological processinositol phosphate metabolic process
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0030425Cellular componentdendrite
GO_0042731Molecular functionPH domain binding
GO_0052658Molecular functioninositol-1,4,5-trisphosphate 5-phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0052659Molecular functioninositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
GO_0004445Molecular functioninositol-polyphosphate 5-phosphatase activity

IV. Literature review

[source]
Gene nameINPP5A
Protein nameINPP5A protein
inositol-polyphosphate 5-phosphatase (EC 3.1.3.56)
Inositol polyphosphate-5-phosphatase A
Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (43 kDa inositol polyphosphate 5-phosphatase) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase)
Synonyms5PTASE
DescriptionFUNCTION: Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate . Plays a crucial role in the survival of cerebellar Purkinje cells (By similarity). .

AccessionsENST00000368593.7
Q4VAR4
B1AP38
Q149S6
ENST00000445580.1
Q5T1B5
Q9C055
ENST00000423490.5
H0Y2W5
Q5T1B3
Q14642
Q86V83
ENST00000368594.8
ENST00000342652.6