INMT report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of INMT at tissue level.

III. Associated gene sets

GO_0009636Biological processresponse to toxic substance
GO_0032259Biological processmethylation
GO_0009308Biological processamine metabolic process
GO_0005829Cellular componentcytosol
GO_0008170Molecular functionN-methyltransferase activity
GO_0030748Molecular functionamine N-methyltransferase activity
GO_0102707Molecular functionS-adenosyl-L-methionine:beta-alanine N-methyltransferase activity
GO_0004790Molecular functionthioether S-methyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameINMT
Protein nameHCG2044801 (Indolethylamine N-methyltransferase)
INMT protein
Indolethylamine N-methyltransferase (Indolamine N-methyltransferase) (EC 2.1.1.49) (EC 2.1.1.96) (Aromatic alkylamine N-methyltransferase) (Amine N-methyltransferase) (Arylamine N-methyltransferase) (Thioether S-methyltransferase) (TEMT)
SynonymshCG_2044801
tcag7.895
DescriptionFUNCTION: Functions as a thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds (By similarity). Catalyzes the N-methylation of tryptamine and structurally related compounds. .

AccessionsQ3MIB5
O95050
ENST00000013222.5 [O95050-1]
ENST00000409539.1 [O95050-2]
A0A090N7V3