ILVBL report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ILVBL at tissue level.

III. Associated gene sets

GO_0009099Biological processvaline biosynthetic process
GO_0009097Biological processisoleucine biosynthetic process
GO_0001561Biological processfatty acid alpha-oxidation
GO_0016020Cellular componentmembrane
GO_0005948Cellular componentacetolactate synthase complex
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0030976Molecular functionthiamine pyrophosphate binding
GO_0003984Molecular functionacetolactate synthase activity
GO_0016829Molecular functionlyase activity
GO_0005515Molecular functionprotein binding
GO_0050660Molecular functionflavin adenine dinucleotide binding
GO_0000287Molecular functionmagnesium ion binding

IV. Literature review

[source]
Gene nameILVBL
Protein nameIlvB acetolactate synthase like
2-hydroxyacyl-CoA lyase 2 (EC 4.1.2.-) (Acetolactate synthase-like protein) (IlvB-like protein)
2-hydroxyacyl-CoA lyase 2 (Acetolactate synthase-like protein) (IlvB-like protein)
SynonymsAHAS
HACL2
DescriptionFUNCTION: Endoplasmic reticulum 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the phytosphingosine degradation pathway. .

AccessionsM0R1B5
ENST00000527093.5
ENST00000534378.5
E9PL44
ENST00000600984.5
ENST00000598709.1
M0R026
A1L0T0
ENST00000533148.5
M0QZX5
ENST00000263383.8
ENST00000533747.1
E9PNL1
E9PJS0